Regulation of proteostasis by glycosylation of nucleocytoplasmic proteins.
Regulation of proteostasis by glycosylation of nucleocytoplasmic proteins.
批准号:
372076
负责人:
Vocadlo David
金额:
$57.96万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2022-09-01
中文摘要
所有生物体的细胞都需要适应环境的变化。一种能够适应环境变化的机制,包括营养可利用性和细胞应激源(如热)的变化,是细胞调节其l - 1的能力
英文摘要
The cells of all organisms need to adapt to changes in their environment. One mechanism enabling adaptation to environmental changes, including variation in nutrient availability and cellular stressors such as heat, is the ability of cells to tune their l
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Selective non-carbohydrate GBA2 inhibitors and their evaluation in models of Batten Disease.
-
批准号:462565
-
项目类别:Operating Grants
-
资助金额:$33.16万
-
财政年份:2022
-
负责人:Vocadlo David
-
依托单位:
Regulation of cellular proteostasis by glycosylation of nucleocytoplasmic proteins.
-
批准号:351779
-
项目类别:Operating Grants
-
资助金额:$7.29万
-
财政年份:2016
-
负责人:Vocadlo David
-
依托单位:
Glycosylation of hydroxymethylcytosine in mammalian genomes - distribution and functional roles.
-
批准号:345292
-
项目类别:Operating Grants
-
资助金额:$54.3万
-
财政年份:2016
-
负责人:Vocadlo David
-
依托单位:
CANADA RESEARCH CHAIRHOLDER - Tier 1 / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA - Niveau 1
-
批准号:302751
-
项目类别:
-
资助金额:$101.99万
-
财政年份:2013
-
负责人:Vocadlo David
-
依托单位:
Generation of effective carbohydrate-based inhibitors of a glycosidase implicated in Alzheimer disease and their molecular mechanism of action.
-
批准号:255267
-
项目类别:Operating Grants
-
资助金额:$38.51万
-
财政年份:2012
-
负责人:Vocadlo David
-
依托单位:
海外基金