Biological activity and mechanisms of peptides derived from oat proteins

人体维持氧化还原平衡的能力在过量氧化剂分子的存在下受到损害。这可能发生在食用氧化食物时，在感染或接触过渡金属期间，所有这些都会增加活性氧物质（即自由基）的产生。这种氧化还原失衡涉及几种慢性疾病的病因，包括癌症、心血管疾病和黄斑变性。具有抗氧化活性的化合物可以防止食物的氧化变质，并减少与上述慢性疾病相关的风险因素。虽然谷物的消费与一些与年龄有关的疾病的发病率下降有关，但造成所观察到的影响的食物成分的性质及其作用机制尚未得到很好的界定。

The ability of the human body to maintain a redox balance is compromised in the presence of excess oxidant molecules. This can occur when oxidized foods is consumed, during infection or exposure to transition metals all of which, increased the production of reactive oxygen species (i.e. free radicals). This redox imbalance is involved in the etiology of several chronic diseases including cancer, cardiovascular diseases and macular degeneration. Compounds that have antioxidant activities can prevent oxidative deterioration of foods and also reduce the risk factors associated with the above chronic ailments. Although, the consumption of cereals is correlated with a decreased incidence of some of age-related diseases, the nature of food ingredients responsible for the observed effects and their mechanisms of action are not well defined.