Apple proanthocyanidins and their metabolites: mechanisms of action in biological systems

加拿大面临着与人类饮食直接或间接相关的人口慢性和代谢性疾病流行病的重大挑战。经常食用富含水果和蔬菜的饮食一直与促进有益的生理功能有关，从而促进人体健康和健康。这些健康益处归功于具有生物活性的植物性多酚化合物，尤其是水果和蔬菜中常见的类黄酮。大量的流行病学研究强烈表明，习惯性

Canada faces significant challenges from population chronic and metabolic disease epidemics, which are directly or indirectly linked to the human diet. The regular consumption of diets rich in fruits and vegetables has been consistently associated with the promotion of beneficial physiological functions leading to human health and wellness. These health benefts have been attributed to biologically active, plant–based polyphenolic compounds, especially flavonoids, commonly found in fruits and vegetables. A large body of epidemilogical studies has strongly suggested that habitual