RAS-MAPK signal transduction in normal and cancer cells
RAS-MAPK signal transduction in normal and cancer cells
批准号:
368336
负责人:
Therrien Marc
金额:
$238.44万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-09-01 至 2024-09-01
关键词:
中文摘要
RAS蛋白是细胞分裂的关键调节因子。值得注意的是,超过三分之一的人类癌症与RAS基因的激活突变有关,这使得它们成为最常见的突变癌基因。然而,尽管作出了相当大的努力,
英文摘要
RAS proteins are key regulators of cell division. Significantly, over a third of human cancers are associated with activating mutations in RAS genes, which makes them the most frequently mutated oncogenes. Yet, despite considerable efforts, there are stil
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Canada Research Chair - Tier 1
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批准号:375890
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项目类别:
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资助金额:$101.99万
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财政年份:2017
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负责人:Therrien Marc
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依托单位:
Intra and intermolecular interactions regulating RAF family members
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批准号:356121
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项目类别:Operating Grants
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资助金额:$62.42万
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财政年份:2016
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负责人:Therrien Marc
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依托单位:
Inner workings of the Ras/MAPK pathway
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批准号:240288
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项目类别:Operating Grants
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资助金额:$62.76万
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财政年份:2011
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负责人:Therrien Marc
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依托单位:
The role of CNK in RTK-dependent signaling
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批准号:212132
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项目类别:Operating Grants
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资助金额:$63.66万
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财政年份:2010
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负责人:Therrien Marc
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依托单位:
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
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批准号:183577
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项目类别:
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资助金额:$36.43万
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财政年份:2008
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负责人:Therrien Marc
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依托单位:
Characterization of the leukemia-inducing NUP98-HOXA9 oncogene using Drosophila and mouse models
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批准号:171939
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项目类别:Operating Grants
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资助金额:$52.58万
-
财政年份:2008
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负责人:Therrien Marc
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依托单位:
海外基金