Investigating a Regulator of the Retromer Sorting Pathway to Develop Therapeutic Targets in Late-Onset Parkinson's Disease
Investigating a Regulator of the Retromer Sorting Pathway to Develop Therapeutic Targets in Late-Onset Parkinson's Disease
批准号:
386493
负责人:
Shortill Shawn P
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-12-01 至 2018-12-01
中文摘要
协调和及时地将蛋白质货物运送到预定的细胞目的地是正常细胞功能的重要组成部分,对这些分选途径的干扰可能导致疾病。例如,逆转录排序途径为i
英文摘要
The coordinated and timely delivery of protein cargos to their intended cellular destinations is an important part of normal cellular function, and perturbations to these sorting pathways can result in disease. The retromer sorting pathway, for example, i
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