Preliminary Studies for Point-Of-Care Immunoassay

医疗点测试是在临床实验室之外和在接受治疗的患者的附近，例如在医院的家庭、医生办公室和急诊科进行的医疗诊断测试。在不需要复杂的实验室设备和基础设施的情况下进行诊断测试的能力对于包括癌症、心脏病和病毒感染在内的许多健康状况非常重要。这项提议旨在开发一种新技术，利用制造硅微芯片所开发的方法来执行护理点诊断测试，这种方法可以被改装成能够精确控制极少量液体的流动。这一能力使复杂的生化分析能够在便携式、低成本和自动化系统中执行，患者和护理人员可以在护理点使用该系统。

Point-of-care tests are medical diagnostic tests performed outside of clinical laboratories and in close proximityof patients receiving care, such as at homes, doctor's offices, and emergency departments in hospitals. Theability to perform diagnostic tests without requiring sophisticated laboratory equipment and infrastructure isimportant for many health conditions including cancer, heart disease, and viral infections. This proposal aimsto develop a new technology to perform point-of-care diagnostic tests utilizing methods developed formanufacturing silicon microchips, which can be adapted to enable precise control over the flow of extremelysmall volumes of liquid. This capability enables sophisticated biochemical analyses to be performed inportable, low-cost, and automated system, which can be utilized by patients and care providers at the point ofcare.