Future Industries Research - Biotechnology and Nanotechnology: Small talk: Communication networks in microbes

我们将使用澳大利亚蛋白质组分析设施来研究微生物相互作用的多方面机制，并产生关于铜绿假单胞菌的新知识，这是囊性纤维化患者的常见死亡原因。我们将描述铜绿假单胞菌和新出现的真菌病原体橙色栅孢菌之间的相互作用，作为更好地了解病原体交流的积极步骤。对病原体相互作用的更好理解应有助于开发新型抗粘连剂作为治疗药物。我们的项目将对年轻科学家进行一种新的综合生物学方法的培训。

We will use the Australian Proteome Analysis Facility to address the multifaceted mechanisms of microbial interactions and produce new knowledge about the pathogen Pseudomonas aeruginosa, a common cause of death in cystic fibrosis patients. We will characterise the interactions between P. aeruginosa and the emerging fungal pathogen Scedosporium aurantiacum as a proactive step towards better understanding of pathogen communication. Improved understanding of pathogen interactions should facilitate the development of novel anti-adhesives as therapeutics. Our project will train young scientists in a new integrated approach to biology.