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Developing a Genome-Wide Platform to Profile Antibiotic Targets and to Identify Novel Bioactive Scaffolds Effective Against Antibiotic-Resistant Pathogens

Developing a Genome-Wide Platform to Profile Antibiotic Targets and to Identify Novel Bioactive Scaffolds Effective Against Antibiotic-Resistant Pathogens
开发全基因组平台来分析抗生素靶标并识别有效对抗抗生素耐药病原体的新型生物活性支架
批准号：
396596
负责人：
Hogan Andrew M
金额：
$10.93万
依托单位：
University of Manitoba
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=396596&lang=en
关键词：
Antibiotic Targets And Resistance Bioinformatics Chemogenomics Chemoinformatics Genetic Networks Gram-Negative Pathogens Machine Learning Next-Generation Sequencing Novel Antimicrobials Transposon Mutagenesis

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中文摘要
翻译
由于抗生素耐药性，药物治疗许多致命疾病的能力正在下降。这对革兰氏阴性菌尤其令人担忧，因为革兰氏阴性菌对许多目前使用的抗生素具有很高的天然耐药性。制药公司很少
英文摘要
The ability of drugs to treat many deadly diseases is decreasing due to antibiotic resistance. This is especially worrisome for Gram-negative bacteria, which have high natural resistance to many currently used antibiotics. Pharmaceutical companies rarely
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Developing a Genome-Wide Platform to Profile Antibiotic Targets and to Identify Novel Bioactive Scaffolds Effective Against Antibiotic-Resistant Pathogens
  • 批准号：
    404089
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2018
  • 负责人：
    Hogan Andrew M
  • 依托单位：
    University of Manitoba
Chemogenomic determination of the mechanism of action of a novel drug against multidrug resistant Burkholderia cenocepacia complex
  • 批准号：
    367131
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2016
  • 负责人：
    Hogan Andrew M
  • 依托单位：
    University of Manitoba
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