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Environmental Radiobiology

Environmental Radiobiology
环境放射生物学
批准号:
CRC-2017-00228
负责人:
Mothersill, Carmel
金额:
$14.57万
依托单位:
依托单位国家:
加拿大
项目类别:
Canada Research Chairs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-01-01 至 2019-12-31

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中文摘要
翻译
该提议旨在研究辐射诱导的旁观者信号的物理传输以及辐射与物质初始相互作用之后的下游事件所涉及的现象和机制。我们已经证明,最初的事件发生时,不需要转移或共享细胞之间的液体介质排除了一个完全的化学机制。该提案的主要目标是阐明信号转导中涉及的生物物理、生物化学和生物能量学途径,但其结果应确定辐射防护和癌症治疗的新目标,并应产生放射生物学的新概念。
英文摘要
This proposal seeks to investigate the phenomenology and mechanisms involved in the physical transmission of radiation induced bystander signals and downstream events subsequent to the initial interaction of radiation with matter. We have demonstrated that the initial events occur without the need for transfer or sharing of liquid medium between cells precluding a wholly chemical mechanism. The elucidation of biophysical, biochemical and bioenergetics pathways involved in signal transduction is the main objective of the proposal, however the results should identify new targets for radiation protection and for cancer therapy and should result in new concepts in radiobiology.
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Environmental Radiobiology
  • 批准号:
    CRC-2017-00228
  • 项目类别:
    Canada Research Chairs
  • 资助金额:
    $14.57万
  • 财政年份:
    2022
  • 负责人:
    Mothersill, Carmel
  • 依托单位:
Physical transmission of bystander signals following ionising radiation exposure
  • 批准号:
    RGPIN-2017-06223
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $5.25万
  • 财政年份:
    2021
  • 负责人:
    Mothersill, Carmel
  • 依托单位:
Environmental Radiobiology
  • 批准号:
    CRC-2017-00228
  • 项目类别:
    Canada Research Chairs
  • 资助金额:
    $14.57万
  • 财政年份:
    2021
  • 负责人:
    Mothersill, Carmel
  • 依托单位:
Physical transmission of bystander signals following ionising radiation exposure
  • 批准号:
    RGPIN-2017-06223
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.62万
  • 财政年份:
    2020
  • 负责人:
    Mothersill, Carmel
  • 依托单位:
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