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Calcium Sensing Receptor (CaSR) Signaling in the Thick Ascending Limb (TAL): Delineating the Pathways Perturbed in Kidney Stone Formers

Calcium Sensing Receptor (CaSR) Signaling in the Thick Ascending Limb (TAL): Delineating the Pathways Perturbed in Kidney Stone Formers
粗升肢 (TAL) 中的钙敏感受体 (CaSR) 信号传导:描绘肾结石形成者中受干扰的通路
批准号:
401370
负责人:
Alexander Robert T
金额:
$69.38万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-03-01 至 2024-03-01

项目摘要

项目成果

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中文摘要
翻译
肾结石很常见,痛苦且治疗费用昂贵。肾结石最常见的危险因素是尿中钙过多。这项提议的主要目的是了解为什么有些人尿钙过多,从而增加了他们的风险
英文摘要
Kidney stones are common, painful and expensive to treat. The most common risk factor for kidney stones is peeing too much calcium. The primary goal of this proposal is to understand why some individuals pee too much calcium, thereby increasing their risk
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会议论文
Leveraging a large cohort of patients with a unique, frequent renal sodium phosphate cotransporter, SLC34A3, pathogenic variation to understand and treat osteoporosis and kidney stones
  • 批准号:
    494218
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Alexander Robert T
  • 依托单位:
KRESCENT 2.0 HRTP Application for a SPOR Supplement: Proposal - SPOR Supplement
  • 批准号:
    463798
  • 项目类别:
    Directed Grant
  • 资助金额:
    $10.93万
  • 财政年份:
    2022
  • 负责人:
    Alexander Robert T
  • 依托单位:
Kidney Research Scientist Core Education and Training Program 2.0
  • 批准号:
    458410
  • 项目类别:
    Operating Grants
  • 资助金额:
    $174.84万
  • 财政年份:
    2021
  • 负责人:
    Alexander Robert T
  • 依托单位:
Canada Research Chair - Tier 2
  • 批准号:
    453867
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2020
  • 负责人:
    Alexander Robert T
  • 依托单位:
海外基金