Linking dynamics to scaling laws in physical and biological systems
Linking dynamics to scaling laws in physical and biological systems
批准号:
RGPIN-2019-05443
负责人:
vanVeen, Lennaert
金额:
$1.38万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-01-01 至 2021-12-31
中文摘要
这个发现项目包括非线性动力学和统计学交叉的三个相互关联的研究方向。我将考虑流体湍流、界面生长和细胞的运动性。在这些现象中,复杂的非线性动力学产生了随时间、空间或实现平均的数量的鲁棒性。在流体湍流中,连贯结构的连续形成和破裂共同产生了著名的柯尔莫哥洛夫能量在空间尺度上分布的幂律。Kolmogorov的理论表明,相干结构以一种自相似的方式相互作用,但这种相互作用的动力学性质仍然不为人所知。在研究界面生长时,我们遇到了相反的问题。在Kuramoto和Sivashinsky的模型中,我们确切地知道会发生什么动态变化。令人惊讶的是,这些动态导致的统计行为是一个悬而未决的问题。35年前,Yakhot推测该模型的统计性质与大量界面生长随机模型的统计性质相同。完全确定的Kuramoto-Sivashinsky模型从根本上来说比流体湍流模型更简单,但迄今为止还没有确凿的证据支持这一猜想。我们将使用尖端的,基于gpu的计算动力系统理论实现来揭示这些经典问题的新亮点,这些问题已经经受了几十年的理论和数值研究。
英文摘要
This Discovery program comprises three interrelated directions of research in the intersection of nonlinear dynamics and statistics. I will consider fluid turbulence, interface growth and the motility of cells. In each of these phenomena, intricate nonlinear dynamics give rise to robust properties of quantities averaged over time, space or realizations. In fluid turbulence, the continuous formation and breakdown of coherent structures conspire to produce, on average, the famous Kolmogorov power law for the distribution of energy over spatial scales. Kolmogorov's theory suggests that the coherent structures interact in a self-similar fashion, but the dynamical nature of such interaction remains ill-understood. In the study of interface growth, we encounter the opposite problem. In a model due to Kuramoto and Sivashinsky, we know precisely what dynamics to expect. Surprisingly, it is an open question what statistical behaviour these dynamics result in. Over thirty-five years ago, Yakhot conjectured that the statistical properties of the model are the same as those of a wide class of stochastic models of interface growth. The entirely deterministic Kuramoto-Sivashinsky model is fundamentally simpler than that of fluid turbulence, yet no conclusive evidence to support the conjecture has been produced to date. We will use cutting-edge, GPU-based implementations of computational dynamical systems theory to shed new light on these classical problems, that have withstood decades of theoretical and numerical study.
The mathematical description of cell motility is much younger than that of fluid turbulence and interface formation. Since experiments have revealed details of individual cell motion, a common modelling approach is agent-based simulation. In this approach, one simulates individual cells and the way they interact, for instance by colliding and aligning. Such simulations can exhibit the formation of clusters of cells that move in unison. However, even with the aid of GPU computing, we can only simulate microscopically small clusters, while in a Petri dish much larger colonies are formed. The challenge is to formulate a locally averaged, continuous model of cluster formation, closer in spirit to equations for fluid motion than to agent-based models. The study of such continuous models will allow us to predict macroscopic properties of collective motion and better understand the formation of biofilms observed, for instance, on medical implants inside the human body.
The questions under consideration lie at the forefront of research in continuum mechanics and will require an innovative mixture of fluid physics, dynamical systems theory and scientific computing to answer. Students on all levels will benefit from the interdisciplinary training opportunities, including modern computational techniques, and be prepared for the ever growing demand for quantitative analysis and optimization of complex processes on the Canadian job market.
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Linking dynamics to scaling laws in physical and biological systems
-
批准号:RGPIN-2019-05443
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$1.38万
-
财政年份:2022
-
负责人:vanVeen, Lennaert
-
依托单位:
Linking dynamics to scaling laws in physical and biological systems
-
批准号:RGPIN-2019-05443
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$1.38万
-
财政年份:2021
-
负责人:vanVeen, Lennaert
-
依托单位:
Model identification for homeostatic data**
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批准号:537690-2018
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项目类别:Engage Grants Program
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资助金额:$1.74万
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财政年份:2018
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负责人:vanVeen, Lennaert
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依托单位:
Transition and pattern formation in physical and physiological systems
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批准号:355849-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
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财政年份:2017
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负责人:vanVeen, Lennaert
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依托单位:
Transition and pattern formation in physical and physiological systems
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批准号:355849-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
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财政年份:2015
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负责人:vanVeen, Lennaert
-
依托单位:
Transition and pattern formation in physical and physiological systems
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批准号:355849-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
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财政年份:2014
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负责人:vanVeen, Lennaert
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依托单位:
Transition and pattern formation in physical and physiological systems
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批准号:355849-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
-
财政年份:2013
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负责人:vanVeen, Lennaert
-
依托单位:
Parsing complex spatio-temporal dynamics in physical and physiological applications
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批准号:355849-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.17万
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财政年份:2012
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负责人:vanVeen, Lennaert
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依托单位:
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