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Suppression of powdery mildew and other plant pathogens, and cleaning of resin-fouled equipment in the cannabis industry

Suppression of powdery mildew and other plant pathogens, and cleaning of resin-fouled equipment in the cannabis industry
抑制白粉病和其他植物病原体,以及清洁大麻行业中树脂污染的设备
批准号:
571078-2021
负责人:
Trant, John
金额:
$2.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Alliance Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
已结题
起止时间:
2021-01-01 至 2022-12-31

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中文摘要
翻译
这个三方项目旨在开发一种具有强大抗菌和抗真菌活性的生物相容配方的新配方,同时还能够防止粘性树脂在农具上堆积。植物病原体从一种植物转移到另一种植物的方式之一是搭便车,搭乘农业工人使用的工具。如果工具可以在两次使用之间轻松清洁,这将大大降低风险,还可以延长工具的使用寿命,减少传统清洁方案所需的停机时间。不幸的是,大多数有效的杀菌剂都是剧毒的,不能用于农业行业的某些领域,如大麻种植。这是所有大麻公司都面临的挑战,总部设在安大略省圣托马斯的Mera Cannabis正在与温莎大学的Trant实验室合作,预防性地解决这个问题。Trant实验室一直在与位于温莎的商业化合作伙伴Prodigie-Innovation Event一起创新具有强大抗病毒和抗菌活性的无酒精洗手液。然而,这些产品不具备这种应用所需的物理性能。该研究小组专门研究纳米乳液的配方,并研究材料的稳定性和机械性能。在这个为期一年的项目中,合作伙伴正在共同努力,开发一种符合行业需求的配方,同时成为一种可行的商业化产品,并建立在坚实的科学基础上。这一为期一年的项目由NSERC和安大略省创新中心以及两个工业合作伙伴共同支持,因此不仅旨在解决加拿大温室产业面临的挑战,而且还旨在创造一种新的加拿大设计和制造的产品,该产品将准备好进入出口市场,因为这将是同类产品中的第一款。该项目由药物化学家约翰·特朗领导,他的团队包括专门研究产品配方、抗真菌和抗微生物活性的科学家。再加上梅拉科学至上的栽培方法,以及Prodigie在创新产品商业化方面的专业知识,这三家合作伙伴处于有利地位,可以提供创新的新材料。
英文摘要
This three-party project aims at developing a new formulation of a biocompatible formulation with potent antimicrobial and antifungal activity while also being able to prevent the buildup of tacky resins on agricultural tools. One of the ways plant pathogens transfer from one plant to another is by "hitchhiking" on tools used by agricultural workers. If tools can be easily cleaned between uses, this would greatly reduce risk and also extend the lifetime of the tools and decrease downtime needed for conventional cleaning protocols. Unfortunately, most potent fungicides are highly toxic and can't be used in certain parts of the agricultural industry like cannabis cultivation. This is a challenge faced by all cannabis companies, and Mera Cannabis, based in St. Thomas Ontario, is working with the Trant Lab at the University of Windsor to address this problem prophylactically. The Trant lab has been innovating alcohol-free hand sanitizers with potent antiviral and antibacterial activity with commercialization partner, Windsor-based, Prodigie - Innovation Evolved. These products do not, however, have the physical properties needed for this application. The research team specializes in formulating nanoemulsions and studying the stability and mechanical properties of the materials. In this one year project, the partners are working together to develop a formulation that meets the needs of the industry while being a viable commercialization product, and based on a sound scientific footing. This one-year project, jointly supported by NSERC and the Ontario Centre of Innovation along with both industrial partners consequently aims not only to solve a challenge facing the greenhouse industry in Canada, but also to create a new designed and made in Canada product that will be ready for the export market, as it would be the first product of its type. The project is led by medicinal chemist John Trant, and his team that includes scientists specializing in product formulation, and antifungal and antimicrobial activity. Coupled with Mera's science-first approach to cultivation, and Prodigie's expertise in innovative product commercialization, the three partners are well positioned to deliver an innovative new material.
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Bioorganic and Biomaterials chemistry: Increasing the stability of carbohydrates, decreasing the stability of peptides
  • 批准号:
    RGPIN-2018-06338
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
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  • 财政年份:
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  • 负责人:
    Trant, John
  • 依托单位:
Bioorganic and Biomaterials chemistry: Increasing the stability of carbohydrates, decreasing the stability of peptides
  • 批准号:
    RGPIN-2018-06338
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2021
  • 负责人:
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  • 依托单位:
Understanding mechanism of action: Combined computational and structural biology studies to determine small molecule effects on protein dynamics and function
  • 批准号:
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  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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  • 负责人:
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  • 批准号:
    566878-2021
  • 项目类别:
    Alliance Grants
  • 资助金额:
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  • 财政年份:
    2021
  • 负责人:
    Trant, John
  • 依托单位:
海外基金