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O-GlcNAc: specificity of modification and impact on protein condensation

O-GlcNAc: specificity of modification and impact on protein condensation
O-GlcNAc:修饰的特异性及其对蛋白质缩合的影响
批准号:
469987
负责人:
Forman-Kay Julie D
金额:
$76.63万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-09-01 至 2027-09-01

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中文摘要
翻译
蛋白质是活细胞的主力,通常被一种名为O-连接N-乙酰氨基葡萄糖(O-GlcNAc)的糖分子修饰。用这种糖修饰蛋白质会促进许多不同癌症的发生。反之,O-GlcNAc S
英文摘要
Proteins, the workhorses of living cells, are often modified by a type of sugar molecule called O-linked N-acetylglucosamine (O-GlcNAc). Modification of proteins with this sugar promotes development of a number of different cancers. Conversely, O-GlcNAc s
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Regulation of mRNA translation and deadenylation by phase separation of autism spectrum disorder-associated proteins
  • 批准号:
    479319
  • 项目类别:
    Operating Grants
  • 资助金额:
    $73.84万
  • 财政年份:
    2023
  • 负责人:
    Forman-Kay Julie D
  • 依托单位:
Canada Research Chair - Tier 1
  • 批准号:
    459670
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2021
  • 负责人:
    Forman-Kay Julie D
  • 依托单位:
Discrete dynamic complexes and phase-separated states of disordered proteins in neurobiology
  • 批准号:
    334016
  • 项目类别:
    Operating Grants
  • 资助金额:
    $103.88万
  • 财政年份:
    2015
  • 负责人:
    Forman-Kay Julie D
  • 依托单位:
Canada Research Chair Tier 1
  • 批准号:
    335749
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2015
  • 负责人:
    Forman-Kay Julie D
  • 依托单位:
国内基金
海外基金
Computational Methods for Analyzing Toponome Data