HIGH FREQUENCY ULTRASOUND FOR EXPERIMENTAL PHYSIOLOGY IN SMALL VERTEBRATES

我们的多学科研究人员团队在研究发育，生殖，压力和心肺机制方面具有专业知识，要求获得资金，以采购最先进的高频超声成像设备，以支持各种研究和培训计划。有没有其他单位或设备具有类似的能力，可在大学或在附近的研究小组。高频超声设备将通过提供活体动物（小至斑马鱼、小青蛙或小鼠）的软组织和器官功能的前所未有的细节，显著提高研究产出。该设备将使我们能够研究斑马鱼心脏如何应对压力和环境挑战，了解新的激素如何调节性器官，制定繁殖稀有和濒危两栖动物的策略，并了解内分泌干扰化学物质如何作用于性腺。我们的HQP将提供一个宝贵的机会，用于复杂成像方法和大型数据集分析所需的尖端培训，适用于动物发育和生理学以及生殖生物学等领域。我们为我们的HQP提供协作和包容的环境。他们将受到学术界，工业界或政府研究部门的高度追捧，因为他们在我们的研究计划中获得了独特的实践培训和可转移的技能。

Our multidisciplinary team of researchers with expertise in studying developmental, reproductive, stress and cardiorespiratory mechanisms requests funding to procure a state-of-the-art high frequency ultrasound imaging device to support diverse research and training programs. There is no other unit or equipment with similar capabilities available at the University or in the vicinity that is accessible by the research team. The high frequency ultrasound equipment will significantly increase research output by providing unprecedented details of soft tissue and organ function in living animals as small as a zebrafish, a tiny frog or a mouse. The equipment will allow us to study how the zebrafish heart responds to stress and environmental challenges, to understand how novel hormones regulate sex organs, to develop strategies to breed rare and endangered amphibians, and to understand how endocrine-disrupting chemicals act on the gonads. Our HQP will be provided with an invaluable opportunity for the cutting-edge training needed for complex imaging methods and large dataset analysis as applied to fields such as animal development and physiology and reproductive biology. We provide a collaborative and inclusive environment for our HQP. They will be highly sought after by academia, industry, or government research departments because of the unique hands-on training and transferable skills that they gain in our research program.