Biomarker Immobilized Organic Electrolyte Gated Field Effect Transistor (BIOEGFET)
Biomarker Immobilized Organic Electrolyte Gated Field Effect Transistor (BIOEGFET)
批准号:
577526-2022
负责人:
Prakash, RaviR
金额:
$1.09万
依托单位:
依托单位国家:
加拿大
项目类别:
Idea to Innovation
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-01-01 至 2023-12-31
中文摘要
我们的新型生物传感器技术Biomarker固定化有机电解液门控场效应晶体管(BIOEGFET)的灵感来自于迫切需要一种用于分析人体动态平衡的点式首次接触筛查工具,以取代传统的只能提供单点且往往不够准确的诊断结果的ELISA法。我们的技术专注于改善患者结局、减少样本到结果的时间表以及优化实验室测试的医疗支出,能够对唾液等非侵入性生物液体中的激素、代谢物和其他生物分析物进行多路重复测试。这种多路生物传感器将传统实验室测试收集的单个数据点扩展为多个数据点的整体和信息量图,训练有素的操作员可以使用这些数据点来识别潜在的假阳性。BIOEGFET系统非常适合在分散的实验室环境、救护车、医生诊所或药房等中间测试环境以及资源有限的环境(如加拿大的偏远社区)中快速检测唾液中的多分析物。
英文摘要
Our novel biosensor technology, the Biomarker Immobilized Organic Electrolyte Gated Field Effect Transistor (BIOEGFET), is inspired by the urgent need for a point-of-care, first contact screening tool for analyzing body homeostasis as a replacement of, or in conjunction with, the traditional ELISA test which only provides a single point and often insufficiently accurate diagnostic outcomes. Shaped by the focus on improving patient outcomes, reducing sample to result timeline, and optimizing medical expenditure on lab tests, our technology is capable of multiplexed and repeat testing of hormones, metabolites, and other bioanalytes in non-invasive bio-fluids such as saliva. Such multiplexed biosensors expand the single data point collected by a conventional laboratory test into a holistic and informative picture of multiple data points that well trained operators can use to identify potential false positives. BIOEGFET systems are highly suited for rapid, multi-analyte sensing in saliva at de-centralized lab settings, intermediate test settings such as an ambulance, a physician's clinic or pharmacies, as well as in resource-limited settings such as remote communities in Canada.
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