Optimizing An Ex Vivo Organ Perfusion of the Mouse Pancreas to Generate a Type I Diabetes Model
Optimizing An Ex Vivo Organ Perfusion of the Mouse Pancreas to Generate a Type I Diabetes Model
批准号:
486225
负责人:
Ping Yvonne
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
1型糖尿病(T1D)是一种自身免疫性疾病,破坏产生胰岛素的β细胞,并且无法治愈。疾病建模有助于理解病理生理学和开发潜在的治疗方法。目前,链脲佐菌素(STZ)被用于治疗糖尿病。
英文摘要
Type 1 diabetes (T1D) is an autoimmune disease that destroys insulin-producing beta cells and has no cure. Disease modelling aids the understanding of the pathophysiology and developing potential therapeutics. Currently, streptozotocin (STZ) is used to ge
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