课题基金 / 基金详情

Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.

Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.
确定参与促进乳腺癌休眠逃逸的分子和环境因素。
批准号:
488246
负责人:
Muller William J
金额:
$83.04万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01

项目摘要

项目成果

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相关文献

中文摘要
翻译
乳腺癌仍然是加拿大妇女第二大致命癌症,其发病率主要归因于复发性肿瘤患者的复发。进入休眠状态的肿瘤最终会重新激活,并经常产生耐药性,
英文摘要
Breast cancer remains the second deadliest cancer for Canadian women and its morbidity is largely attributed to relapse in patients from recurrent tumors. Tumors that enter a state of dormancy can eventually reactivate and often confer drug resistance and
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会议论文
Chi3L1 (YKL-40) plays a multifaceted role in modulating tumor immune microenvironment during breast cancer progression.
  • 批准号:
    478513
  • 项目类别:
    Operating Grants
  • 资助金额:
    $93.07万
  • 财政年份:
    2023
  • 负责人:
    Muller William J
  • 依托单位:
Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.
  • 批准号:
    483129
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Muller William J
  • 依托单位:
Identification of Stat1 signaling pathway(s) involved in mediating tumor escape from immune surveillance.
  • 批准号:
    490747
  • 项目类别:
    Operating Grants
  • 资助金额:
    $4.55万
  • 财政年份:
    2023
  • 负责人:
    Muller William J
  • 依托单位:
The multifaceted role of c-Src tyrosine kinase in breast cancer progression.
  • 批准号:
    468470
  • 项目类别:
    Operating Grants
  • 资助金额:
    $83.6万
  • 财政年份:
    2022
  • 负责人:
    Muller William J
  • 依托单位:
国内基金
海外基金
2C型蛋白磷酸酶REDUCED DORMANCY 5通过激酶-磷酸酶蛋白复合体调控种子休眠的分子机制