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Detecting and preventing epigenetic defects and adverse health outcomes associated with assisted reproduction

Detecting and preventing epigenetic defects and adverse health outcomes associated with assisted reproduction
检测和预防与辅助生殖相关的表观遗传缺陷和不良健康结果
批准号:
489634
负责人:
Trasler Jacquetta M
金额:
$68.27万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01

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中文摘要
翻译
辅助生殖技术(ART)占高收入国家活产的1-6%。虽然大多数使用抗逆转录病毒疗法受孕的儿童是健康的,但据报道,出生缺陷和异常健康结果的增加。这些不良后果,
英文摘要
Assisted reproductive technologies (ART) account for 1-6% of live births in high income countries. While most children conceived using ART are healthy, increases in birth defects and abnormal health outcomes have been reported. Such adverse outcomes assoc
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会议论文
Sex-specific susceptibility windows for fetal origins of adult disease and intergenerational effects
Assisted Reproductive Technologies and Folic Acid Supplementation: Gene-environment Interactions and Neurodevelopmental and Metabolic Outcomes in Children
Sex-specific susceptibility windows for fetal origins of adult disease and transgenerational effects
Mechanisms of regulation of gene expression in the mammalian germline
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