Prevalence and risk factors of depression in Chinese patients with type 2 diabetes mellitus: a protocol of systematic review and meta-analysis.
Prevalence and risk factors of depression in Chinese patients with type 2 diabetes mellitus: a protocol of systematic review and meta-analysis.
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中国2型糖尿病患者抑郁症患病率及危险因素：系统评价和荟萃分析方案
DOI：
10.1186/s13643-021-01855-7
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发表时间：
2021-11-25
影响因子：
3.7
通讯作者：
Jin R
中科院分区：
文献类型：
--
作者：
Liu X;Dong C;Jiang H;Zhong D;Li Y;Zhang H;Zhang J;Fan J;Li J;Guan L;Jin R
中国2型糖尿病（T2 DM）的患病率正在上升。抑郁症是T2 DM的一个重要并发症，导致T2 DM的管理不善。因此，早期发现和治疗T2 DM患者的抑郁症是必要和有效的。因此，我们计划进行系统回顾和荟萃分析，以评估中国T2 DM患者抑郁的患病率，并探讨T2 DM抑郁的潜在危险因素。我们将检索MEDLINE、EMBASE、科克伦图书馆、中国生物医学文献数据库（CBM）、中国知网（CNKI）、中文科技期刊数据库（VIP）和万方数据库中自成立以来的文献。我们将手动搜索灰色文献、已识别研究的参考文献列表、相关网站，并咨询该领域的专家。我们将纳入基于人群的横断面调查，调查中国T2 DM患者抑郁的患病率或/和T2 DM患者抑郁的可能危险因素。两名评审员将筛选研究，提取数据，并独立评估偏倚风险。将使用美国医疗保健研究和质量管理局方法检查表评估偏倚风险。如果可行，我们将对观察数据进行随机效应荟萃分析，以总结汇总患病率，并使用分类数据的比值比来探索潜在的危险因素。患病率估计值将根据年龄、性别和其他因素进行分层。将使用Cochran Q和I2指数估计统计异质性。我们将进行荟萃回归以调查异质性的潜在来源，进行敏感性分析以评估合成结果的稳健性，并进行漏斗图和Egger检验以评估发表偏倚。本系统综述和荟萃分析将为中国T2 DM患者抑郁症的患病率和潜在危险因素提供全面的证据。希望能为医护人员和政策制定者关注T2 DM患者的心理健康提供依据。我们的数据将强调早期发现和干预T2 DM患者抑郁的必要性和重要性。PROSPERO CRD 42020182979。在线版本包含补充材料，可通过10.1186/s13643-021-01855-7获得。
The prevalence of type 2 diabetes mellitus (T2DM) is growing in China. Depression is a significant complication of T2DM, leading to poor management of T2DM. Thus, early detection and treatment of depression in patients with T2DM are essential and effective. Therefore, we plan to conduct a systematic review and meta-analysis to evaluate the prevalence of depression in Chinese patients with T2DM and explore potential risk factors of depression in T2DM. We will search literatures recorded in MEDLINE, EMBASE, the Cochrane Library, Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), and WanFang Database from their inception onwards. We will manually search gray literatures, reference lists of identified studies, relevant websites, and consult experts in this field. We will include population-based, cross-sectional surveys that investigated the prevalence of depression in Chinese patients with T2DM or/and the possible risk factors of depression in T2DM. Two reviewers will screen studies, extract data, and evaluate risk of bias independently. Agency for Healthcare Research and Quality methodology checklist will be used to assess the risk of bias. If feasible, we will conduct random effects meta-analysis of observational data to summarize the pooled prevalence, and use odds ratio for categorical data to explore potential risk factors. Prevalence estimates will be stratified according to age, gender, and other factors. Statistical heterogeneity will be estimated using Cochran’s Q and I2 index. We will conduct meta-regression to investigate the potential sources of heterogeneity, sensitivity analyses to assess robustness of the synthesized results, and funnel plots and Egger’s test to assess publication bias. This systematic review and meta-analysis will provide comprehensive evidence of the prevalence and potential risk factors of depression in Chinese patients with T2DM. We expect to provide evidence for healthcare practitioners and policy makers to pay attention to the mental health of patients with T2DM. Our data will highlight the need and importance of early detection and intervention for depression in patients with T2DM. PROSPERO CRD42020182979. The online version contains supplementary material available at 10.1186/s13643-021-01855-7.
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影响因子：
8.2
作者：
Nouwen, A.;Winkley, K.;Twisk, J.;Lloyd, C. E.;Peyrot, M.;Ismail, K.;Pouwer, F.
通讯作者：
Pouwer, F.
影响因子：
16.2
作者：
Nouwen A;Nefs G;Caramlau I;Connock M;Winkley K;Lloyd CE;Peyrot M;Pouwer F;European Depression in Diabetes Research Consortium
通讯作者：
European Depression in Diabetes Research Consortium
影响因子：
11.3
作者：
Hussain, Salman;Habib, Anwar;Najmi, Abul Kalam
通讯作者：
Najmi, Abul Kalam
影响因子：
8.2
作者：
Pouwer, F.;Tack, C. J.;Geelhoed-Duijvestijn, P. H. L. M.;Bazelmans, E.;Beekman, A. T.;Heine, R. J.;Snoek, F. J.
通讯作者：
Snoek, F. J.
影响因子：
4.4
作者：
Roy T;Lloyd CE;Parvin M;Mohiuddin KG;Rahman M
通讯作者：
Rahman M