An fMRI study of sentence-embedded lexical-semantic decision in children and adults.
An fMRI study of sentence-embedded lexical-semantic decision in children and adults.
复制标题
对儿童和成人的词法词法词语决定的fMRI研究。
DOI：
10.1016/j.bandl.2010.03.009
复制
发表时间：
2010-08
影响因子：
2.5
通讯作者：
Mueller, Ralph-Axel
中科院分区：
文献类型：
--
作者：
Moore-Parks, Erin Nicole;Burns, Erin L.;Bazzill, Rebecca;Levy, Sarah;Posada, Valerie;Mueller, Ralph-Axel
词汇-语义知识是语言的核心组成部分，在整个儿童时期都经历了长期的发展，因此非常适合于发展研究。以前的大多数词汇-语义功能磁共振(FMRI)研究都局限于句子上下文之外的单词或词对任务。我们的目标是调查词汇-语义语言网络的发展，在典型的发育儿童中，使用更生态的嵌入句子的语义任务，允许执行监控，同时通过避免公开言语来最大限度地减少头部移动。16名成人和23名儿童完成了两次听觉词汇-语义判断任务的fMRI测试，其中包括按下按钮的反应，并使用反向语音作为控制条件。儿童和成人在双侧颞叶和左侧额叶下部表现出相似的激活。在左侧顶下区、运动前区和额下区，以及双侧辅助运动区(SMA)，成人比儿童有更大的激活。特别是对于语义不一致的句子，成年人在左下额叶皮质表现出比儿童更大的激活，这可能与加强自上而下的控制有关。运动相关区域的年龄依赖性激活增加与显性运动反应无关，但可能与伴随语义决定的隐性言语有关。与以前的研究不同，在后部感觉皮质(如纹外皮质)和颞中回没有检测到年龄相关的差异。
Lexical-semantic knowledge is a core language component that undergoes prolonged development throughout childhood and is therefore highly amenable to developmental studies. Most previous lexical-semantic functional MRI (fMRI) studies have been limited to single-word or word-pair tasks, outside a sentence context. Our objective was to investigate the development of lexical-semantic language networks in typically developing children using a more ecological sentence-embedded semantic task that permitted performance monitoring while minimizing head movement by avoiding overt speech. Sixteen adults and 23 children completed two fMRI runs of an auditory lexical-semantic decision task with a button-press response, using reverse speech as control condition. Children and adults showed similar activation in bilateral temporal and left inferior frontal regions. Greater activation in adults than in children was seen in left inferior parietal, premotor, and inferior frontal regions, and in bilateral supplementary motor area (SMA). Specifically for semantically incongruous sentences, adults also showed greater activation than children in left inferior frontal cortex, possibly related to enhanced top-down control. Age-dependent activation increases in motor-related regions were shown to be unrelated to overt motor responses, but could be associated with covert speech accompanying semantic decision. Unlike previous studies, age-dependent differences were not detected in posterior sensory cortices (such as extrastriate cortex), nor in middle temporal gyrus.
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影响因子：
5.7
作者：
Holland, SK;Plante, E;Ball, WS
通讯作者：
Ball, WS
影响因子：
4.8
作者：
Gaillard, WD;Sachs, BC;Grandin, CB
通讯作者：
Grandin, CB
影响因子：
2.5
作者：
Burton, MW;Noll, DC;Small, SL
通讯作者：
Small, SL
影响因子：
2.7
作者：
Holland, Scott K.;Vannest, Jennifer;Byars, Anna W.
通讯作者：
Byars, Anna W.
DOI：
10.3758/bf03204507
发表时间：
1993-05-01
期刊：
BEHAVIOR RESEARCH METHODS INSTRUMENTS & COMPUTERS
影响因子：
--
作者：
COHEN, J;MACWHINNEY, B;PROVOST, J
通讯作者：
PROVOST, J