Novel human astroviruses in pediatric respiratory samples: A one-year survey in a Swiss tertiary care hospital.
Novel human astroviruses in pediatric respiratory samples: A one-year survey in a Swiss tertiary care hospital.
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DOI：
10.1002/jmv.25246
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发表时间：
2018-11
影响因子：
12.7
通讯作者：
Kaiser L
中科院分区：
文献类型：
--
作者：
Cordey S;Zanella MC;Wagner N;Turin L;Kaiser L
尽管已知经典人类星状病毒 (HAstV) 是病毒性胃肠炎的主要原因，但新型 HAstV 的发病机制和临床表现仍然很大程度上未知。越来越多的证据表明，与经典星状病毒相比，新型 HAstV 表现出上呼吸道的趋向性。这一一年的患病率使用实时逆转录聚合酶链反应对从 ≤5 岁儿童患者收集的所有可用临床鼻咽拭子样本进行了新型和经典 HAstV 筛查。总共测试了205个样品；检测到两例新的 HAstV 病例，患病率为 1.3%，病毒载量表明上呼吸道复制活跃。未检测到经典 HAstV。
Although classical human astroviruses (HAstV) are known to be a leading cause of viral gastroenteritis, the pathogenesis and clinical manifestations of novel HAstV remain largely unknown. There is mounting evidence that, in contrast to classical astroviruses, novel HAstV exhibit tropism for the upper respiratory tract. This one‐year period prevalence screened all available clinical nasopharyngeal swab samples collected from pediatric patients aged ≤5 years for novel and classical HAstV using real‐time reverse transcription polymerase chain reaction. A total of 205 samples were tested; two novel HAstV cases were detected for a prevalence of 1.3%, with viral loads suggesting active upper respiratory tract replication. No classical HAstV was detected.
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影响因子：
4.8
作者：
Meyer CT;Bauer IK;Antonio M;Adeyemi M;Saha D;Oundo JO;Ochieng JB;Omore R;Stine OC;Wang D;Holtz LR
通讯作者：
Holtz LR
影响因子：
1.3
作者：
Pereira, Elaine;Marion, Robert
通讯作者：
Marion, Robert
影响因子：
8.8
作者：
Sato, Masanori;Kuroda, Makoto;Tanaka-Taya, Keiko
通讯作者：
Tanaka-Taya, Keiko
影响因子：
12.7
作者：
Khamrin, Pattara;Thongprachum, Aksara;Ushijima, Hiroshi
通讯作者：
Ushijima, Hiroshi
影响因子：
13.2
作者：
Cordey, Samuel;Vu, Diem-Lan;Kaiser, Laurent
通讯作者：
Kaiser, Laurent