Childhood Obesity Risk and Prevention: Shining a Lens on the First 1000 Days.
Childhood Obesity Risk and Prevention: Shining a Lens on the First 1000 Days.
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儿童肥胖风险与预防：关注前 1000 天。
DOI：
10.1089/chi.2016.0088
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Taveras,ElsieM
中科院分区：
文献类型：
--
作者：
Taveras,ElsieM
最初的 1000 天（从受孕到 2 岁的时期）越来越被认为是肥胖及其不良后果发生和预防的重要时期。近年来，美国国家科学院、工程院、医学院 1 和 NIH2 召开了多学科研讨会，以研究科学现状和有希望的解决方案，以降低从生命早期开始的儿童肥胖风险。此外，世界卫生组织终止儿童肥胖委员会的报告3强调了孕前、产前和儿童早期在预防儿童肥胖方面的重要作用，罗伯特伍德约翰逊基金会最近发布了一份关于前 1000 天对儿童肥胖影响的问题简报。 4 然而，对于生命早期肥胖发展的病因学以及合理的行为和生物学机制的理解仍然存在巨大的知识差距，并且几乎没有采取干预措施来证明生命早期的预防对婴儿生长状态和肥胖相关行为的有益影响程度。对于本期《儿童肥胖》主题，我们要求来自多个学科的研究人员提交文章，以推进生命早期肥胖危险因素的科学发展。 和预防。总而言之，本期的文章开始缩小证据差距，并提出新兴且有前景的方法和途径，以进一步为从生命早期开始预防肥胖提供信息。 Claesson 和同事 5 Fuemmeler 和同事 6 以及 Gregory 和同事 7 检查了妊娠的危险因素和干预措施。 Fuemmeler 及其同事使用平移和旋转叠加 (SITAR) 方法检查了母亲孕前肥胖和妊娠期体重增加与婴儿出生后 24 个月体重轨迹的关联，该方法提供了婴儿体型、达到峰值速度的时间和生长速度的估计值。孕前肥胖和妊娠期体重增加是否足够是独立的。
The first 1000 days—the period from conception to age 2 years—is increasingly recognized as an important period for the development, and thus prevention, of obesity and its adverse consequences. In recent years, the National Academies of Sciences, Engineering, and Medicine1 and the NIH2 have convened multidisciplinary workshops to examine the state of the science and promising solutions to reduce the risk of childhood obesity beginning in early life. Additionally, The World Health Organization’s Report of the Commission on Ending Childhood Obesity3 emphasized the important role of the preconception, antenatal, and early childhood periods in prevention of childhood obesity, and the Robert Wood Johnson Foundation recently published an issue brief on the impact of the first 1000 days on childhood obesity. 4 Yet, substantial knowledge gaps remain in the understanding of etiology and plausible behavioral and biological mechanisms of obesity development in early life, and few interventions have been conducted to demonstrate the extent to which prevention in early life has a beneficial effect on infant growth status and obesity-related behaviors.For this theme issue of Childhood Obesity, we asked investigators from a range of disciplines to submit articles that advanced the science of early life obesity risk factors and prevention. Taken together, the articles in this issue begin to narrow the evidence gaps and present emerging and promising methods and approaches to further inform obesity prevention beginning in early life. Claesson and colleagues, 5 Fuemmeler and colleagues, 6 and Gregory and colleagues7 examined risk factors and interventions in pregnancy. Fuemmeler and colleagues examined associations of maternal prepregnancy obesity and gestational weight gain with infant weight trajectories in the first 24 months of life using the SuperImposition by Translation and Rotation (SITAR) method, which provides estimates of infant size, timing to peak velocity, and growth velocity. Both prepregnancy obesity and greaterthan-adequate gestational weight gain were indepen-
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