Different interaction modes for the default mode network revealed by resting state functional magnetic resonance imaging
Different interaction modes for the default mode network revealed by resting state functional magnetic resonance imaging
复制标题
静息态功能磁共振成像揭示默认模式网络的不同交互模式
DOI：
10.1111/ejn.13112
复制
发表时间：
2016-01
影响因子：
3.4
通讯作者：
Jiang, Tianzi
中科院分区：
文献类型：
--
作者：
Song, Ming;Fan, Lingzhong;Eickhoff, Simon B.;Jiang, Tianzi
默认模式网络(DMN)在静息状态下，既负责大脑的内在化，又负责对外界刺激的反射反应，被认为是人脑中的重要网络。条件化和反射性反应这两个角色对DMN节点和其他任务网络的招募是不同的。现有研究表明，DMN内部(DMN内节点之间)和DMN外(DMN内节点与任务网络中节点之间)的相互作用在强度和时间方面都有不同的模式。这些发现提出了一些有趣的问题。例如，DMN的内部和外部相互作用是线性的还是非线性的？这项研究使用人类连接组项目的数据集检查了这些交互模式。利用基于最大信息的非参数勘探统计策略来刻画全相关性，并利用皮尔逊相关性来捕捉全相关性的线性分量。然后，我们对比了DMN的内部和外部相互作用的线性/非线性水平。经过全脑的探索，我们发现DMN和感觉运动相关网络(包括感觉运动、感觉联系和整合区域)之间的相互作用表现出更多的非线性，而DMN内节点之间的相互作用同样表现出较少的非线性。这些发现可能为理解DMN的内部和外部作用的潜在神经元原理提供线索。
The default mode network (DMN), which, in the resting state, is in charge of both the brain's intrinsic mentation and its reflexive responses to external stimuli, is recognized as an essential network in the human brain. These two roles of mentation and reflexive response recruit the DMN nodes and other task networks differently. Existing research has revealed that the interactions inside the DMN (between nodes within the DMN) and outside the DMN (between nodes in the DMN and nodes in task networks) have different modes, in terms of both strength and timing. These findings raise interesting questions. For example, are the internal and external interactions of the DMN equally linear or nonlinear? This study examined these interaction patterns using datasets from the Human Connectome Project. A maximal information‐based nonparametric exploration statistics strategy was utilized to characterize the full correlations, and the Pearson correlation was used to capture the linear component of the full correlations. We then contrasted the level of linearity/nonlinearity with respect to the internal and external interactions of the DMN. After a brain‐wide exploration, we found that the interactions between the DMN and the sensorimotor‐related networks (including the sensorimotor, sensory association, and integration areas) showed more nonlinearity, whereas those between the intra‐DMN nodes were similarly less nonlinear. These findings may provide a clue for understanding the underlying neuronal principles of the internal and external roles of the DMN.
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DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Fox, MD;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
影响因子：
5.7
作者：
Van Essen, David C.;Smith, Stephen M.;Barch, Deanna M.;Behrens, Timothy E. J.;Yacoub, Essa;Ugurbil, Kamil
通讯作者：
Ugurbil, Kamil
DOI：
10.1177/1073858411403316
发表时间：
2012-06
期刊：
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
影响因子：
--
作者：
Andrews-Hanna JR
通讯作者：
Andrews-Hanna JR
影响因子：
2.9
作者：
Hartman, D.;Hlinka, J.;Corbetta, M.
通讯作者：
Corbetta, M.
使用扩散张量成像对人类颞极进行基于连通性的分割
影响因子：
3.7
作者：
Fan, Lingzhong;Wang, Jiaojian;Jiang, Tianzi
通讯作者：
Jiang, Tianzi