Probabilistic MRI brain anatomical atlases based on 1,000 Chinese subjects.

Probabilistic MRI brain anatomical atlases based on 1,000 Chinese subjects.
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基于 1,000 名中国受试者的概率 MRI 脑解剖图谱

DOI:
10.1371/journal.pone.0050939
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Li K
Li K
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Wang X;Chen N;Zuo Z;Xue R;Jing L;Yan Z;Shen D;Li K

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脑地图集旨在为神经科学研究提供一个标准的大脑参考坐标系。现有的人脑图谱被广泛用于提供有关大脑结构特征的解剖学参考和信息。然而,他们中的大多数来自西方人口中的一名患者或一小部分样本。这对东方学科的科学研究构成了限制。在这项研究中,使用基于HAMMER(弹性配准分层属性匹配机制)的MR解剖图像,构建了10个不同年龄和性别的新的中文脑图谱。共有1000名年龄在18岁到70岁之间的中国志愿者参与了这项研究。这些特定于人群的脑图谱代表了中国人口的基本结构特征。它们可用于基础神经科学研究和临床诊断,包括对中国和其他东方国家患者的神经和神经精神障碍的评估。
Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.
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