Probabilistic MRI brain anatomical atlases based on 1,000 Chinese subjects.
Probabilistic MRI brain anatomical atlases based on 1,000 Chinese subjects.
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基于 1,000 名中国受试者的概率 MRI 脑解剖图谱
DOI:
10.1371/journal.pone.0050939
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Li K
中科院分区:
文献类型:
--
作者:
Wang X;Chen N;Zuo Z;Xue R;Jing L;Yan Z;Shen D;Li K
Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.
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