Association between Maternal Characteristics and Immune Factors TGF-β1, TGF-β2, and IgA in Colostrum: An Exploratory Study in Japan.
Association between Maternal Characteristics and Immune Factors TGF-β1, TGF-β2, and IgA in Colostrum: An Exploratory Study in Japan.
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母亲特征与初乳中免疫因子TGF-β1、TGF-β2和伊加的关系:日本的探索性研究。
DOI:
10.3390/nu14163255
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发表时间:
2022-08-09
期刊:
影响因子:
5.9
通讯作者:
Yoshida K
中科院分区:
文献类型:
--
作者:
Hirata N;Kiuchi M;Pak K;Fukuda R;Mochimaru N;Mitsui M;Yoshida K
Colostrum is the first food for newborns and it contains various crucial immune factors. The concentrations of immune factors in breast milk may change depending on maternal characteristics such as body mass index, collection day, and age at first pregnancy. In this exploratory study, we investigated the association between TGF-β1, TGF-β2, and IgA in colostrum and rarely studied factors that affect breast milk components, including the use of labor-inducing medication, colostrum secretion, sex of newborns, breast or nipple problems, and nipple care. Breast milk samples were collected from 42 mothers and analyzed for TGF-β1, TGF-β2, and IgA. The results suggest that parity and mode of delivery may be correlated with the concentrations of immune factors in colostrum. However, we found no association between the immune factors in colostrum and the use of labor-inducing medications, colostrum secretion, sex of newborns, breast or nipple problems, and nipple care. These findings have some implications for further analysis of the effects of immune factors in breast milk on the prognosis of allergies in children.
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