A wheat kinase and immune receptor form host-specificity barriers against the blast fungus.

A wheat kinase and immune receptor form host-specificity barriers against the blast fungus.
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DOI:
10.1038/s41477-023-01357-5
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发表时间:
2023-03
期刊:
影响因子:
18
通讯作者:
Nicholson, Paul
Nicholson, Paul
中科院分区:
生物学1区
文献类型:
--
作者:
Arora, Sanu;Steed, Andrew;Goddard, Rachel;Gaurav, Kumar;O'Hara, Tom;Schoen, Adam;Rawat, Nidhi;Elkot, Ahmed F. F.;Korolev, Andrey V. V.;Chinoy, Catherine;Nicholson, Martha H. H.;Asuke, Soichiro;Antoniou-Kourounioti, Rea;Steuernagel, Burkhard;Yu, Guotai;Awal, Rajani;Forner-Martinez, Macarena;Wingen, Luzie;Baggs, Erin;Clarke, Jonathan;Saunders, Diane G. O.;Krasileva, Ksenia V. V.;Tosa, Yukio;Jones, Jonathan D. G.;Tiwari, Vijay K. K.;Wulff, Brande B. H.;Nicholson, Paul

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自1985年在巴西出现以来,小麦稻瘟病已蔓延到整个南美洲,最近在孟加拉国和赞比亚也出现了。在这里,我们表明,两个小麦抗性基因,Rwt3和Rwt4,作为主机特异性障碍,对非小麦稻瘟病致病型编码的核苷酸结合富含亮氨酸重复免疫受体和串联激酶,分别。这些基因的分子分离将使病原体效应基因和宿主抗性基因之间的分子相互作用的研究成为可能。这项研究确定了两个基因,这两个基因对保护小麦免受稻瘟病菌的侵害很重要,稻瘟病菌也会感染相关的禾本科植物。这项工作有助于确定培育小麦的潜在策略,提高对这种破坏性真菌的抗性。
Since emerging in Brazil in 1985, wheat blast has spread throughout South America and recently appeared in Bangladesh and Zambia. Here we show that two wheat resistance genes, Rwt3 and Rwt4, acting as host-specificity barriers against non-Triticum blast pathotypes encode a nucleotide-binding leucine-rich repeat immune receptor and a tandem kinase, respectively. Molecular isolation of these genes will enable study of the molecular interaction between pathogen effector and host resistance genes. This study identifies two genes that are important for protecting wheat against blast fungus, a pathogen that also infects related grasses. This work helps identify potential strategies for breeding wheat with improved resistance to this damaging fungus.
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