Reactome knowledgebase of human biological pathways and processes.

Reactome knowledgebase of human biological pathways and processes.
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DOI:
10.1093/nar/gkn863
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发表时间:
2009-01
影响因子:
14.9
通讯作者:
D'Eustachio P
D'Eustachio P
中科院分区:
生物学2区
文献类型:
--
作者:
Matthews L;Gopinath G;Gillespie M;Caudy M;Croft D;de Bono B;Garapati P;Hemish J;Hermjakob H;Jassal B;Kanapin A;Lewis S;Mahajan S;May B;Schmidt E;Vastrik I;Wu G;Birney E;Stein L;D'Eustachio P

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Reactome(http://www.reactome.org)是由专家撰写的人类反应和途径的知识库,可作为数据挖掘资源和电子教科书。目前的发布包括2975种人类蛋白质,2907个反应和4455个文献引用。一个新的实体级途径查看器和改进的搜索和数据挖掘工具促进了搜索和可视化路径数据以及用户提供的高通量数据集的分析。 Reactome通过改进的矫正预测方法提高了对模型生物体的效用,从而允许对22种物种进行途径推断,并通过协作来创建手动策划的Reactome途径数据集,用于包括拟南芥,Oryza sativa(Rice),Drosophilla和Gallus(Gallus)(鸡肉)。 Reactome的数据内容和软件都可以在开源条款下自由使用和重新分布。
Reactome (http://www.reactome.org) is an expert-authored, peer-reviewed knowledgebase of human reactions and pathways that functions as a data mining resource and electronic textbook. Its current release includes 2975 human proteins, 2907 reactions and 4455 literature citations. A new entity-level pathway viewer and improved search and data mining tools facilitate searching and visualizing pathway data and the analysis of user-supplied high-throughput data sets. Reactome has increased its utility to the model organism communities with improved orthology prediction methods allowing pathway inference for 22 species and through collaborations to create manually curated Reactome pathway datasets for species including Arabidopsis, Oryza sativa (rice), Drosophila and Gallus gallus (chicken). Reactome's data content and software can all be freely used and redistributed under open source terms.
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影响因子: 14.9
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