Antibacterial activity of some selected medicinal plants of Pakistan.
Antibacterial activity of some selected medicinal plants of Pakistan.
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DOI：
10.1186/1472-6882-11-52
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发表时间：
2011-06-30
影响因子：
--
通讯作者：
Zia M
中科院分区：
文献类型：
--
作者：
Bibi Y;Nisa S;Chaudhary FM;Zia M
筛选民族植物是评价其治疗潜力的先决条件，它可以导致新的生物活性化合物的分离。采用琼脂孔扩散法，对6种重要药用植物（黄南星、水麻、虎尾树、阿月浑子、七叶树和红椿）的粗提物和提取部位进行了抗3种革兰氏阳性和2种革兰氏阴性ATCC细菌的活性测定。全缘毛白杨和A. Indica对所有测试的细菌菌株都有活性（12-23 mm的抑制区）。另外4种植物的粗提物（黄南星、水麻、乌藨子和红椿）对不同的细菌菌株均有抑制作用。粗提物表现出不同程度的杀菌活性。A.印楝和全缘商陆粗提物对B的活性最高（分别为19.66和16 mm）。subtilis的氯仿组分，而T. ciliata和D.柳叶菜对所有测试的细菌培养物表现出良好的抗菌活性（13-17 mm的抑制区）。阿月浑子的甲醇部分、水麻和红椿的氯仿部分以及七叶树的水溶性部分是开发新型抗菌化合物的合适候选物。
Screening of the ethnobotenical plants is a pre-requisite to evaluate their therapeutic potential and it can lead to the isolation of new bioactive compounds. The crude extracts and fractions of six medicinal important plants (Arisaema flavum, Debregeasia salicifolia, Carissa opaca, Pistacia integerrima, Aesculus indica, and Toona ciliata) were tested against three Gram positive and two Gram negative ATCC bacterial species using the agar well diffusion method. The crude extract of P. integerrima and A. indica were active against all tested bacterial strains (12-23 mm zone of inhibition). Other four plant's crude extracts (Arisaema flavum, Debregeasia salicifolia, Carissa opaca, and Toona ciliata) were active against different bacterial strains. The crude extracts showed varying level of bactericidal activity. The aqueous fractions of A. indica and P. integerrima crude extract showed maximum activity (19.66 and 16 mm, respectively) against B. subtilis, while the chloroform fractions of T. ciliata and D. salicifolia presented good antibacterial activities (13-17 mm zone of inhibition) against all the bacterial cultures tested. The methanol fraction of Pistacia integerrima, chloroform fractions of Debregeasia salicifolia &Toona ciliata and aqueous fraction of Aesculus indica are suitable candidates for the development of novel antibacterial compounds.
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影响因子：
5.4
作者：
Kamuhabwa, A;Nshimo, C;de Witte, P
通讯作者：
de Witte, P
影响因子：
5.4
作者：
Malairajan, P.;Gopalakrishnan, Geetha;Kavimani, S.
通讯作者：
Kavimani, S.
影响因子：
--
作者：
Ahameethunisa AR;Hopper W
通讯作者：
Hopper W
DOI：
10.1080/10575630290033088
发表时间：
2002-10-01
期刊：
NATURAL PRODUCT LETTERS
影响因子：
--
作者：
Akbar, E;Malik, A
通讯作者：
Malik, A
影响因子：
1.8
作者：
da Silva, MFGF;Agostinho, SMM;Vieira, PC
通讯作者：
Vieira, PC