Quantitative genetic analysis suggests causal association between cuticular hydrocarbon composition and desiccation survival in Drosophila melanogaster.
Quantitative genetic analysis suggests causal association between cuticular hydrocarbon composition and desiccation survival in Drosophila melanogaster.
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DOI：
10.1038/hdy.2010.40
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发表时间：
2011-01
期刊：
影响因子：
3.8
通讯作者：
Telonis-Scott, M.
中科院分区：
文献类型：
--
作者：
Foley, B. R.;Telonis-Scott, M.
在低相对湿度下生存是一种复杂的适应，在果蝇种群和物种中观察到许多重复的向干燥进化的例子。抗干燥性的一个一般机制是表皮烃（CHC）熔点。本研究首次构建了干旱胁迫下水稻抗脱水性群体水平遗传变异的QTL定位图。黑腹菌利用一组来自单一自然群体的重组自交系（RILs），我们绘制了整个基因组中两性的QTL。我们发现，在两性中，CHCs与抗干燥性密切相关。在大多数抗脱水性位点，CHC与从CHC变异的倾斜模式和脂质的生化性质预测的脱水抗性之间存在显着关联。这种关联在女性中比男性强得多，可能是因为女性中CHCs的总体丰度更高，或者是由于男性中用于防水的CHCs与性信号之间的相关性。CHC的形成可能是D.黑腹果蝇这将是有趣的比较模式的CHC变化和干燥的阻力，适应干燥的物种，和雨林限制物种不能。
Survival to low relative humidity is a complex adaptation, and many repeated instances of evolution to desiccation have been observed among Drosophila populations and species. One general mechanism for desiccation resistance is Cuticular Hydrocarbon (CHC) melting point. We performed the first Quantitative Trait Locus (QTL) map of population level genetic variation in desiccation resistance in D. melanogaster. Using a panel of Recombinant Inbred Lines (RILs) derived from a single natural population, we mapped QTL in both sexes throughout the genome. We found that in both sexes, CHCs correlated strongly with desiccation resistance. At most desiccation resistance loci there was a significant association between CHCs and desiccation resistance of the sort predicted from clinal patterns of CHC variation and biochemical properties of lipids. This association was much stronger in females than males, perhaps because of greater overall abundance of CHCs in females, or due to correlations between CHCs used for waterproofing and sexual signalling in males. CHC evolution may be a common mechanism for desiccation resistance in D. melanogaster. It will be interesting to compare patterns of CHC variation and desiccation resistance in species which adapt to desiccation, and rainforest restricted species which cannot.
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影响因子：
5.2
作者：
Hoffmann, AA;Shirriffs, J;Scott, M
通讯作者：
Scott, M
影响因子：
2.1
作者：
Bubliy, OA;Loeschcke, V
通讯作者：
Loeschcke, V
DOI：
10.1073/pnas.88.16.7257
发表时间：
1991-08-01
影响因子：
11.1
作者：
GIBBS, A;MOUSSEAU, TA;CROWE, JH
通讯作者：
CROWE, JH
DOI：
10.1086/physzool.65.2.30158253
发表时间：
1992-03-01
期刊：
PHYSIOLOGICAL ZOOLOGY
影响因子：
--
作者：
GRAVES, JL;TOOLSON, EC;ROSE, MR
通讯作者：
ROSE, MR
影响因子：
2.1
作者：
HOFFMANN, AA;PARSONS, PA
通讯作者：
PARSONS, PA