Microbiologic Profiles of Patients with Dental Prosthetic Treatment and Periodontitis before and after Photoactivation Therapy-Randomized Clinical Trial.
Microbiologic Profiles of Patients with Dental Prosthetic Treatment and Periodontitis before and after Photoactivation Therapy-Randomized Clinical Trial.
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DOI：
10.3390/microorganisms9040713
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发表时间：
2021-03-30
期刊：
影响因子：
4.5
通讯作者：
Tatarciuc M
中科院分区：
文献类型：
--
作者：
Mocanu RC;Martu MA;Luchian I;Sufaru IG;Maftei GA;Ioanid N;Martu S;Tatarciuc M
固定修复的牙列缺损可能会影响牙周组织，反之亦然，牙周组织会影响牙列缺损的寿命和美观。我们提出了一个调查的总细菌负荷，特定的牙周病原体，牙周临床参数的患者与牙固定修复和不同程度的牙周组织损失，遵循光活化治疗（PDT）洁治和根面平整。该研究对160名受试者进行了研究，这些受试者被随机分配到单独进行洁治和根面平整（SRP）（52名受试者，256个部位）、SRP和氯己定冲洗（58名受试者，276个部位）以及SRP加PDT（50名受试者，318个部位）。牙周参数（菌斑指数，探诊出血，探诊深度和临床附着丧失），其次是总细菌载量和特定的牙周病原体（Aggregatibacteractinomycetemcomitans，牙龈卟啉单胞菌，Tannerella denticola和密螺旋体）在每个患者的基线，1个月和6个月后进行了检查。PDT在1个月后临床和微生物负荷均得到显著改善，并且与单独使用氯己定冲洗或SRP相比，这些结果在6个月后保持不变，特别是在严重牙周炎病例中。光活化治疗作为一种牙周治疗方法，可以有效地为固定义齿患者提供牙周临床和微生物学参数的补充改善，特别是在严重的牙周炎病例中。
Fixed prosthodontic dental restorations can potentially affect the periodontal tissues and vice versa, the periodontium can influence the longevity and esthetic appearance of dental restorations. We proposed an investigation on total bacterial load, specific periodontal pathogens, and periodontal clinical parameters in patients with dental fixed prosthesis and different degrees of periodontal tissue loss that followed photoactivation therapy (PDT) adjunctive to scaling and root planing. The study was conducted on 160 subjects, which were randomly assigned to scaling and root planing (SRP) alone (52 subjects, 256 sites), SRP and chlorhexidine rinsing (58 subjects, 276 sites), and SRP plus PDT (50 subjects, 318 sites). Periodontal parameters (plaque index, bleeding on probing, probing depth, and clinical attachment loss), followed by total bacterial load and specific periodontal pathogens (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola) were examined in each patient at baseline, one and six months after. PDT exerted significant improvements both in clinical and microbiological load after one month, and these results were maintained 6 months after when compared to chlorhexidine rinsing or SRP alone, especially in severe periodontitis cases. Photoactivation therapy as an adjunctive periodontal therapeutic method was efficient in offering supplementary periodontal improvements in the clinical and microbiological parameters of patients with fixed dental prosthesis, particularly in severe periodontitis cases.
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DOI：
10.1126/science.aad3292
发表时间：
2016-01-01
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Baym M;Stone LK;Kishony R
通讯作者：
Kishony R
DOI：
10.1016/s1646-2890(07)70136-x
发表时间：
2007-07-01
影响因子：
0.3
作者：
Carvalho, Carlos;Cabral, Cristina Trigo
通讯作者：
Cabral, Cristina Trigo
影响因子：
2.1
作者：
Queiroz, Adriana C.;Suaid, Flavia Adelino;Souza, Sergio L. S.
通讯作者：
Souza, Sergio L. S.
影响因子：
0.2
作者：
Rakasevic, Dragana;Lazic, Zoran;Aleksic, Zoran
通讯作者：
Aleksic, Zoran
影响因子：
3.5
作者：
Fontana CR;Abernethy AD;Som S;Ruggiero K;Doucette S;Marcantonio RC;Boussios CI;Kent R;Goodson JM;Tanner AC;Soukos NS
通讯作者：
Soukos NS