The anaemia of Plasmodium vivax malaria.
The anaemia of Plasmodium vivax malaria.
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DOI:
10.1186/1475-2875-11-135
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发表时间:
2012-04-27
期刊:
影响因子:
3
通讯作者:
Price RN
中科院分区:
文献类型:
--
作者:
Douglas NM;Anstey NM;Buffet PA;Poespoprodjo JR;Yeo TW;White NJ;Price RN
Plasmodium vivax threatens nearly half the world’s population and is a significant impediment to achievement of the millennium development goals. It is an important, but incompletely understood, cause of anaemia. This review synthesizes current evidence on the epidemiology, pathogenesis, treatment and consequences of vivax-associated anaemia. Young children are at high risk of clinically significant and potentially severe vivax-associated anaemia, particularly in countries where transmission is intense and relapses are frequent. Despite reaching lower densities than Plasmodium falciparum, Plasmodium vivax causes similar absolute reduction in red blood cell mass because it results in proportionately greater removal of uninfected red blood cells. Severe vivax anaemia is associated with substantial indirect mortality and morbidity through impaired resilience to co-morbidities, obstetric complications and requirement for blood transfusion. Anaemia can be averted by early and effective anti-malarial treatment.
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DOI:
10.1086/510756
发表时间:
2007-02-15
期刊:
The Journal of infectious diseases
影响因子:
--
作者:
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通讯作者:
Maguire GP
影响因子:
6.5
作者:
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通讯作者:
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DOI:
10.1098/rspb.2008.0198
发表时间:
2008-06-22
影响因子:
4.7
作者:
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通讯作者:
de Roode, Jacobus C.
DOI:
10.4269/ajtmh.2007.77.984
发表时间:
2007-11-01
影响因子:
3.3
作者:
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通讯作者:
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DOI:
10.1080/00034983.1990.11812429
发表时间:
1990-02-01
影响因子:
--
作者:
BRABIN, BJ;GINNY, M;PAINO, J
通讯作者:
PAINO, J