Gastrointestinal Complications of Obesity.
Gastrointestinal Complications of Obesity.
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DOI：
10.1053/j.gastro.2016.12.052
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发表时间：
2017-05
期刊：
影响因子：
29.4
通讯作者：
Acosta A
中科院分区：
文献类型：
--
作者：
Camilleri M;Malhi H;Acosta A
肥胖通常与糖尿病和心血管疾病相关的发病率有关。然而，肥胖是许多胃肠道和肝脏疾病的直接原因（例如非酒精性脂肪肝病）或显着的危险因素，例如反流性食管炎和胆结石。当肥胖成为危险因素时，它可能与其他机制相互作用，导致早期发病或复杂的疾病。肥胖导致的几种胃肠道并发症的比值比或相对风险增加：胃食管反流病、糜烂性食管炎、巴雷特食管、食管腺癌、糜烂性胃炎、胃癌、腹泻、结肠憩室病、息肉、癌症、肝病（包括非酒精性脂肪肝病）、肝硬化、肝细胞癌、胆结石、急性胰腺炎和胰腺癌。胃肠病学家除了在营养和内窥镜干预方面的专业知识外，还以独特的方式参与肥胖症的多学科管理，作为治疗肥胖相关疾病患者的医生。
Obesity usually is associated with morbidity related to diabetes mellitus and cardiovascular diseases. However, there are many gastrointestinal and hepatic diseases for which obesity is the direct cause (eg, nonalcoholic fatty liver disease) or is a significant risk factor, such as reflux esophagitis and gallstones. When obesity is a risk factor, it may interact with other mechanisms and result in earlier presentation or complicated diseases. There are increased odds ratios or relative risks of several gastrointestinal complications of obesity: gastroesophageal reflux disease, erosive esophagitis, Barrett’s esophagus, esophageal adenocarcinoma, erosive gastritis, gastric cancer, diarrhea, colonic diverticular disease, polyps, cancer, liver disease including nonalcoholic fatty liver disease, cirrhosis, hepatocellular carcinoma, gallstones, acute pancreatitis, and pancreatic cancer. Gastroenterologists are uniquely poised to participate in the multidisciplinary management of obesity as physicians caring for people with obesity-related diseases, in addition to their expertise in nutrition and endoscopic interventions.
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影响因子：
13.5
作者：
Aleksandrova, Krasimira;Boeing, Heiner;Noethlings, Ute;Jenab, Mazda;Fedirko, Veronika;Kaaks, Rudolf;Lukanova, Annekatrin;Trichopoulou, Antonia;Trichopoulos, Dimitrios;Boffetta, Paolo;Trepo, Elisabeth;Westhpal, Sabine;Duarte-Salles, Talita;Stepien, Magdalena;Overvad, Kim;Tjonneland, Anne;Halkjaer, Jytte;Boutron-Ruault, Marie-Christine;Dossus, Laure;Racine, Antoine;Lagiou, Pagona;Bamia, Christina;Benetou, Vassiliki;Agnoli, Claudia;Palli, Domenico;Panico, Salvatore;Tumino, Rosario;Vineis, Paolo;Bueno-De-Mesquita, Bas;Peeters, Petra H.;Gram, Inger Torhild;Lund, Eiliv;Weiderpass, Elisabete;Quiros, J. Ramon;Agudo, Antonio;Sanchez, Maria-Jose;Gavrila, Diana;Barricarte, Aurelio;Dorronsoro, Miren;Ohlsson, Bodil;Lindkvist, Bjoern;Johansson, Anders;Sund, Malin;Khaw, Kay-Tee;Wareham, Nicholas;Travis, Ruth C.;Riboli, Elio;Pischon, Tobias
通讯作者：
Pischon, Tobias
影响因子：
29.4
作者：
Camilleri M
通讯作者：
Camilleri M
影响因子：
7.6
作者：
Anggiansah, R.;Sweis, R.;Fox, M.
通讯作者：
Fox, M.
影响因子：
24.5
作者：
Aro, P;Ronkainen, J;Agréus, L
通讯作者：
Agréus, L
影响因子：
9.8
作者：
Chan, Simon S. M.;Luben, Robert;Hart, Andrew R.
通讯作者：
Hart, Andrew R.