Diminishing risk for age-related macular degeneration with nutrition: a current view.

Diminishing risk for age-related macular degeneration with nutrition: a current view.
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DOI:
10.3390/nu5072405
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发表时间:
2013-07-02
期刊:
影响因子:
5.9
通讯作者:
Taylor A
Taylor A
中科院分区:
医学2区
文献类型:
--
作者:
Schleicher M;Weikel K;Garber C;Taylor A

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年龄相关性黄斑变性(AMD)是老年人失明的主要原因。在工业化国家,老年性黄斑变性的临床特征见于三分之一的老年人。通过饮食调整进行预防性干预是很有吸引力的策略,因为它们比临床治疗更实惠,不需要专家管理,许多研究表明,对于AMD,微量和大量营养素的益处很少,如果有的话,副作用。这篇综述的目的是从最近的文献中提供关于各种营养素的价值的信息,特别是omega-3脂肪酸,降低血糖指数的饮食,也许还有一些类胡萝卜素,在降低AMD发病或进展的风险方面。即将进行的与年龄相关的眼病研究(AREDS) II干预试验的结果应该特别翔实。
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. Clinical hallmarks of AMD are observed in one third of the elderly in industrialized countries. Preventative interventions through dietary modification are attractive strategies, because they are more affordable than clinical therapies, do not require specialists for administration and many studies suggest a benefit of micro- and macro-nutrients with respect to AMD with few, if any, adverse effects. The goal of this review is to provide information from recent literature on the value of various nutrients, particularly omega-3 fatty acids, lower glycemic index diets and, perhaps, some carotenoids, with regard to diminishing risk for onset or progression of AMD. Results from the upcoming Age-Related Eye Disease Study (AREDS) II intervention trial should be particularly informative.
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