Green tea drinking and risk of pancreatic cancer: a large-scale, population-based case-control study in urban Shanghai.
Green tea drinking and risk of pancreatic cancer: a large-scale, population-based case-control study in urban Shanghai.
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DOI：
10.1016/j.canep.2012.08.004
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发表时间：
2012-12
影响因子：
2.6
通讯作者：
Gao, Yu-Tang
中科院分区：
文献类型：
--
作者：
Wang, Jing;Zhang, Wei;Sun, Lu;Yu, Herbert;Ni, Quan-Xing;Risch, Harvey A.;Gao, Yu-Tang
胰腺癌的病因学知之甚少。关于饮茶和胰腺癌风险的流行病学研究尚未得出结论。本研究的目的是调查绿色茶饮用与胰腺癌的风险在上海，中国城市之间的关系。本研究采用病例对照研究方法，在上海市区进行，共收集908例胰腺癌患者和1067例健康对照。通过访谈问卷收集饮茶信息，包括茶的种类、饮茶量、茶的温度和经常饮茶的时间。我们研究了多种饮茶习惯与胰腺癌风险的关系。在女性中，与不经常喝茶的人相比，经常喝绿色茶与胰腺癌风险降低32%相关（OR 0.68，95%CI 0.48-0.96）。增加消费量和更长的饮茶时间都与女性胰腺癌风险降低有关。在经常喝茶的人中，较低的茶温度与男性和女性胰腺癌风险的降低有关，与喝茶的量或持续时间无关。饮用绿色茶的习惯，包括经常饮用，消费量，习惯的持久性和茶的温度，可以降低胰腺癌的风险。
Little is known about the etiology of pancreatic cancer. Epidemiological studies on tea consumption and pancreatic cancer risk have been inconclusive. The purpose of the present study was to investigate the association between green tea drinking and the risk of pancreatic cancer in urban Shanghai, China. In this population-based case-control study conducted in urban Shanghai, 908 cases of pancreatic cancer and 1067 healthy controls were recruited. Information on tea drinking, including type of tea, amount of tea consumption, temperature of tea, and the duration of regular tea drinking, were collected via interview questionnaire. We examined the association of multiple tea drinking habits with the risk of pancreatic cancer. In women, regular green tea drinking was associated with 32% reduction of pancreatic cancer risk (OR 0.68, 95% CI 0.48–0.96), compared to those who did not drink tea regularly. Increased consumption and longer duration of tea drinking were both associated with reduced pancreatic cancer risk in women. Among regular tea drinkers, lower temperature of tea was associated with reduced risk of pancreatic cancer in both men and women, independent of amount or duration of tea drinking. Habits of green tea drinking, including regular drinking, amount of consumption, persistence of the habit, and tea temperature, may lower pancreatic cancer risk.
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影响因子：
254.7
作者：
Jemal, Ahmedin;Siegel, Rebecca;Thun, Michael J.
通讯作者：
Thun, Michael J.
DOI：
10.1038/nrc2641
发表时间：
2009-06
期刊：
Nature reviews. Cancer
影响因子：
--
作者：
通讯作者：
--
影响因子：
6.4
作者：
ZATONSKI, WA;BOYLE, P;WALKER, AM
通讯作者：
WALKER, AM
影响因子：
4.7
作者：
Shu, XO;Yang, G;Zheng, W
通讯作者：
Zheng, W
影响因子：
2.4
作者：
Luo, Juhua;Inoue, Manami;Tsugane, Shoichiro
通讯作者：
Tsugane, Shoichiro