The potential benefits of red beetroot supplementation in health and disease.

The potential benefits of red beetroot supplementation in health and disease.
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DOI:
10.3390/nu7042801
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发表时间:
2015-04-14
期刊:
影响因子:
5.9
通讯作者:
Stevenson EJ
Stevenson EJ
中科院分区:
医学2区
文献类型:
--
作者:
Clifford T;Howatson G;West DJ;Stevenson EJ

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近年来,红甜菜的生物活性及其作为保健和预防疾病的功能食品的潜在应用受到越来越多的关注。作为硝酸盐的一种来源,甜菜根摄取提供了一种增加体内一氧化氮(NO)利用率的自然手段,并已成为预防和管理与NO生物利用率降低相关的病理变化的潜在策略,尤其是高血压和内皮功能。甜菜根也被认为是一种有前景的治疗方法,用于治疗与氧化应激和炎症相关的一系列临床病理。其成分,最著名的是甜菜碱色素,在体外和体内显示出强大的抗氧化、抗炎和化学预防活性。本综述的目的是讨论甜菜根的生物活性,并评估专门研究甜菜根补充剂对炎症、氧化应激、认知和内皮功能影响的研究证据。
In recent years there has been a growing interest in the biological activity of red beetroot (Beta vulgaris rubra) and its potential utility as a health promoting and disease preventing functional food. As a source of nitrate, beetroot ingestion provides a natural means of increasing in vivo nitric oxide (NO) availability and has emerged as a potential strategy to prevent and manage pathologies associated with diminished NO bioavailability, notably hypertension and endothelial function. Beetroot is also being considered as a promising therapeutic treatment in a range of clinical pathologies associated with oxidative stress and inflammation. Its constituents, most notably the betalain pigments, display potent antioxidant, anti-inflammatory and chemo-preventive activity in vitro and in vivo. The purpose of this review is to discuss beetroot’s biological activity and to evaluate evidence from studies that specifically investigated the effect of beetroot supplementation on inflammation, oxidative stress, cognition and endothelial function.
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