A rat brain MRI template with digital stereotaxic atlas of fine anatomical delineations in paxinos space and its automated application in voxel-wise analysis.
A rat brain MRI template with digital stereotaxic atlas of fine anatomical delineations in paxinos space and its automated application in voxel-wise analysis.
复制标题
DOI：
10.1002/hbm.21511
复制
发表时间：
2013-06
影响因子：
4.8
通讯作者：
Shan, Baoci
中科院分区：
文献类型：
--
作者：
Nie, Binbin;Chen, Kewei;Zhao, Shujun;Liu, Junhua;Gu, Xiaochun;Yao, Qunli;Hui, Jiaojie;Zhang, Zhijun;Teng, Gaojun;Zhao, Chunjie;Shan, Baoci
本研究构建了一个包含嗅球的大鼠脑部T2加权磁共振成像模板以及一个与之匹配的数字图谱。该图谱基于帕西诺斯（Paxinos）和沃森（Watson）2005年最新版的大鼠脑图谱，精心描绘了624个脑部结构。作为SPM工具箱的一种自动化程序被引入，用于对单个大鼠脑部进行空间归一化，进行统计分析，并在图谱坐标空间中对结果进行可视化定位。利用右侧大脑中动脉闭塞（MCAO）大鼠和正常对照大鼠之间的功能图像对脑部模板/图谱以及该程序进行了评估。结果表明，MCAO大鼠中信号显著下降的脑区与闭塞位置一致。
This study constructs a rat brain T2-weighted magnetic resonance imaging template including olfactory bulb and a compatible digital atlas. The atlas contains 624 carefully delineated brain structures based on the newest (2005) edition of rat brain atlas by Paxinos and Watson. An automated procedure, as an SPM toolbox, was introduced for spatially normalizing individual rat brains, conducting statistical analysis and visually localizing the results in the Atlas coordinate space. The brain template/atlas and the procedure were evaluated using functional images between rats with the right side middle cerebral artery occlusion (MCAO) and normal controls. The result shows that the brain region with significant signal decline in the MCAO rats was consistent with the occlusion position.
登录
查看更多内容
大鼠脑磁共振成像研究中追踪感兴趣区域的自动方法
影响因子：
4.4
作者：
Nie, Binbin;Hui, Jiaojie;Zhao, Shujun
通讯作者：
Zhao, Shujun
影响因子：
6.3
作者：
Schubert, Carla R.;Carmichael, Lakeesha L.;Murphy, Claire;Klein, Barbara E. K.;Klein, Ronald;Cruickshanks, Karen J.
通讯作者：
Cruickshanks, Karen J.
影响因子：
5.7
作者：
Black, KJ;Snyder, AZ;Perlmutter, JS
通讯作者：
Perlmutter, JS
影响因子：
5.7
作者：
Keller, SS;Wilke, M;Roberts, N
通讯作者：
Roberts, N
影响因子：
5.7
作者：
Black, KJ;Koller, JM;Perlmutter, JS
通讯作者：
Perlmutter, JS