The Impact of Maternal Diet during Pregnancy and Lactation on the Fatty Acid Composition of Erythrocytes and Breast Milk of Chilean Women.
The Impact of Maternal Diet during Pregnancy and Lactation on the Fatty Acid Composition of Erythrocytes and Breast Milk of Chilean Women.
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DOI：
10.3390/nu10070839
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发表时间：
2018-06-28
期刊：
影响因子：
5.9
通讯作者：
Valenzuela A
中科院分区：
文献类型：
--
作者：
Barrera C;Valenzuela R;Chamorro R;Bascuñán K;Sandoval J;Sabag N;Valenzuela F;Valencia MP;Puigrredon C;Valenzuela A
母亲怀孕期间的饮食与胎儿期和哺乳期的脂肪酸供应有关。花生四烯酸（AA）和二十二碳六烯酸（DHA）也与大脑和视觉系统的正常生长和发育有关。母亲提供给胎儿和婴儿的AA和DHA与母亲的饮食摄入和身体储存直接相关。我们的目的是评估产妇饮食的影响，特别是指脂肪酸摄入量的质量，在智利妇女的样本在怀孕的最后阶段和整个哺乳期。50名健康孕妇（年龄范围20-33岁）从怀孕第6个月开始研究，并随访至哺乳期第6个月。通过食物频率问卷调查评估饮食特征。红细胞磷脂和母乳样品的脂肪酸组成进行了评估，通过气液色谱法。总的来说，女性的饱和脂肪酸摄入量较高，单不饱和脂肪酸和多不饱和脂肪酸（PUFA）摄入量充足。膳食中n-6 PUFA含量高，n-3 PUFA含量低（主要是DHA），n-6/n-3 PUFA比例不平衡。哺乳期红细胞和母乳中DHA的浓度显著低于妊娠期，AA中未观察到这种模式。我们的结论是，有必要通过改善食品质量，特别是其DHA含量来增加怀孕和哺乳期间n-3 PUFA的摄入量。
Maternal diet during pregnancy is relevant for fatty acid supply during fetal life and lactation. Arachidonic (AA) and docosahexaenoic (DHA) acids are also relevant for the normal growth and development of brain and visual system. AA and DHA provided by the mother to the fetus and infant are directly associated with maternal dietary intake and body stores. Our aim was to evaluate the impact of maternal diet, specially referring to the quality of fatty acid intake, in a sample of Chilean women during last stage of pregnancy and across the lactation period. Fifty healthy pregnant women (age range 20–33 years) were studied from the 6th month of pregnancy and followed until 6th month of lactation period. Diet characteristics were evaluated through food frequency questionnaires. Fatty acids composition of erythrocyte phospholipids and breast milk samples was assessed by gas-liquid chromatography. Overall, women had high saturated fatty acids intake with sufficient intake of mono- and polyunsaturated fatty acids (PUFA). Diet was high in n-6 PUFA and low in n-3 PUFA (mainly DHA), with imbalanced n-6/n-3 PUFA ratio. Erythrocytes and breast milk DHA concentration was significantly reduced during lactation compared to pregnancy, a pattern not observed for AA. We concluded that is necessary to increase the intake of n-3 PUFA during pregnancy and lactation by improving the quality of consumed foods with particular emphasis on its DHA content.
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影响因子：
3.6
作者：
Birch, EE;Hoffman, DR;Prestidge, C
通讯作者：
Prestidge, C
影响因子：
3.6
作者：
Gil, Angel;Gil, Fernando
通讯作者：
Gil, Fernando
DOI：
10.1016/j.plefa.2017.08.001
发表时间：
2017-09-01
影响因子：
3
作者：
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通讯作者：
Valenzuela, Alfonso
影响因子：
3.2
作者：
Garmendia, Maria L.;Alonso, Faustino T.;Corvalan, Camila
通讯作者：
Corvalan, Camila
DOI：
10.1097/mco.0b013e3282f795e6
发表时间：
2008-05-01
影响因子：
3.1
作者：
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通讯作者：
Koletzko, Berthold