Low 25-hydroxyvitamin D levels in adolescents: race, season, adiposity, physical activity, and fitness.
Low 25-hydroxyvitamin D levels in adolescents: race, season, adiposity, physical activity, and fitness.
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DOI：
10.1542/peds.2009-2055
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发表时间：
2010-06
期刊：
影响因子：
8
通讯作者：
Zhu H
中科院分区：
文献类型：
--
作者：
Dong Y;Pollock N;Stallmann-Jorgensen IS;Gutin B;Lan L;Chen TC;Keeton D;Petty K;Holick MF;Zhu H
目的是了解居住在美国东南部（纬度：北纬 33°）的黑人和白人青少年的维生素 D 状况，并调查其与肥胖的关系。采用液相色谱-串联质谱法测量了 559 名 14 至 18 岁青少年（45% 黑人和 49% 女性）的血浆 25-羟基维生素 D 水平。还测量了脂肪组织、体力活动和心血管健康。维生素D不足（<75nmol/L）和缺乏（≤50nmol/L）的总体患病率分别为56.4%和28.8%。与白人受试者相比，黑人受试者在每个季节的血浆 25-羟基维生素 D 水平均显着降低（冬季，35.9±2.5 vs 77.4±2.7 nmol/L；春季，46.4±3.5 vs 101.3±3.5 nmol/L；夏季，50.7±4.0 vs 104.3±4.0 nmol/L；秋季，54.4±4.0 vs 96.8±2.7 纳摩尔/升）。调整年龄、性别、种族、季节、身高和性成熟度后，25-羟基维生素 D 水平与所有肥胖测量值之间存在显着的负相关，包括 BMI 百分位数 (P=.02)、腰围 (P<.01)、总脂肪量 (P<.01)、体脂百分比 (P <.01)、内脏脂肪组织 (P <.015) 和皮下腹部脂肪组织 (P<.039)。 25-羟基维生素 D 水平与剧烈体力活动 (P <.01) 和心血管健康 (P =.025) 之间存在显着正相关。生活在常年阳光明媚气候的青少年中，尤其是黑人青少年中，维生素 D 水平较低的现象普遍存在。 25-羟基维生素 D 水平、肥胖、体力活动和健康之间的关系似乎存在于青春期。
The objectives were to characterize the vitamin D status of black and white adolescents residing in the southeastern United States (latitude: 33°N) and to investigate relationships with adiposity. Plasma 25-hydroxyvitamin D levels were measured with liquid chromatography-tandem mass spectroscopy for 559 adolescents 14 to 18 years of age (45% black and 49% female). Fat tissues, physical activity, and cardiovascular fitness also were measured. The overall prevalences of vitamin D insufficiency (<75nmol/L) and deficiency (≤50 nmol/L) were 56.4% and 28.8%, respectively. Black versus white subjects had significantly lower plasma 25-hydroxyvitamin D levels in every season (winter, 35.9±2.5 vs 77.4±2.7 nmol/L; spring, 46.4±3.5 vs 101.3±3.5 nmol/L; summer, 50.7±4.0 vs 104.3±4.0 nmol/L; autumn, 54.4± 4.0 vs 96.8±2.7 nmol/L). With adjustment for age, gender, race, season, height, and sexual maturation, there were significant inverse correlations between 25-hydroxyvitamin D levels and all adiposity measurements, including BMI percentile (P=.02), waist circumference (P<.01), total fat mass (P<.01), percentage of body fat (P <.01), visceral adipose tissue (P <.015), and subcutaneous abdominal adipose tissue (P<.039). There were significant positive associations between 25-hydroxyvitamin D levels and vigorous physical activity (P <.01) and cardiovascular fitness (P =.025). Low vitamin D status is prevalent among adolescents living in a year-round sunny climate, particularly among black youths. The relationships between 25-hydroxyvitamin D levels, adiposity, physical activity, and fitness seem to be present in adolescence.
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DOI：
10.1097/00005768-199901000-00022
发表时间：
1999-01-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Owens, S;Gutin, B;Thompson, W
通讯作者：
Thompson, W
影响因子：
1.6
作者：
Rajakumar, K;Fernstrom, JD;Greenspan, SL
通讯作者：
Greenspan, SL
影响因子：
7.1
作者：
Weng, Francis L.;Shults, Justine;Zemel, Babette S.
通讯作者：
Zemel, Babette S.
影响因子：
4
作者：
Harkness, L;Cromer, B
通讯作者：
Cromer, B
影响因子：
5.6
作者：
CHEN, TC;TURNER, AK;HOLICK, MF
通讯作者：
HOLICK, MF