Poor Sleep and Obesity: Concurrent Epidemics in Adolescent Youth.

Poor Sleep and Obesity: Concurrent Epidemics in Adolescent Youth.
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DOI:
10.3389/fendo.2018.00364
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发表时间:
2018
影响因子:
5.2
通讯作者:
Hannon TS
Hannon TS
中科院分区:
医学2区
文献类型:
--
作者:
Gohil A;Hannon TS

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睡眠不足和肥胖在美国青少年中非常普遍,而且往往同时发生。这篇综述探讨了肥胖和睡眠之间的联系,概述了青年人睡眠特征、肥胖和心脏代谢危险因素之间的关系。青少年的睡眠时间不太理想,并且随着年龄的增长而减少。这对整体健康有害,并与儿童,青少年和年轻人的肥胖有关。因此,睡眠时间不足与饮食质量差、胰岛素敏感性降低、高血糖和普遍的心脏代谢危险因素有关。有证据表明,睡眠质量差和昼夜节律改变,其特征是偏好较晚的睡眠开始,称为“青少年时钟类型”,有助于缩短睡眠时间。阻塞性睡眠呼吸暂停(OSA)在肥胖的年轻人中更常见,并且与自主神经系统活动相关,促进血压升高,心血管疾病风险标志物增加和胰岛素抵抗。虽然在成年人中OSA和2型糖尿病之间存在明确的关联,但目前尚不清楚这种关联是否在青年中普遍存在。改善青少年睡眠时间和质量以及肥胖的干预措施很少,需要更多的证据来确定这些干预措施是否可以改善与肥胖相关的健康结果。
Poor sleep and obesity are both extraordinarily common in the US adolescent population and often occur simultaneously. This review explores the links between obesity and sleep, outlining what is known about the relationships between sleep characteristics, obesity, and cardiometabolic risk factors in youth. Sleep duration is less than optimal in teens, and decreases as age increases. This is detrimental to overall well-being and is associated with obesity in children, adolescents, and young adults. Accordingly, inadequate sleep duration is associated with poor diet quality, decreased insulin sensitivity, hyperglycemia, and prevalent cardiometabolic risk factors. Evidence suggests that poor sleep quality and altered circadian timing characterized by a preferred later sleep onset, known as “adolescent chronotype,” contributes to shortened sleep duration. Obstructive sleep apnea (OSA) occurs more frequently among youth with obesity, and is associated with autonomic nervous system activity promoting higher blood pressure, increased markers of cardiovascular disease risk, and insulin resistance. While there is a clear association between OSA and type 2 diabetes in adults, whether or not this association is prevalent in youth is unclear at this time. Interventions to improve both sleep duration and quality, and obesity in adolescents are scarce and more evidence is needed to determine if such interventions can improve obesity-related health outcomes.
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