Genome diversity in arbuscular mycorrhizal fungi.

Genome diversity in arbuscular mycorrhizal fungi.
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丛枝菌根真菌的基因组多样性。

DOI:
10.1016/j.pbi.2015.06.005
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发表时间:
2015
影响因子:
9.5
通讯作者:
Young JP
Young JP
中科院分区:
生物学2区
文献类型:
--
作者:
Young JP

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在丛枝菌根真菌中,多个核共用一个细胞质。在一个分离的细胞核中可能存在基因组多样性。遗传变异相对丰度的变化可能伴随着表型的变化。然而,全基因组测序只发现了适度的变异。线粒体基因组在分离株内的变异更少。丛枝菌根真菌(Glomeromycota)是植物中分布最广、最重要的共生体。它们不能在没有植物的情况下培养,显然是无性的,在一个细胞质中有多个细胞核。有证据表明细胞核之间存在遗传变异,这种变异在生长过程中存在分离,但这些发现仍有争议。最近,两篇论文报道了一株不规则根噬菌的全基因组序列;两者都表明细胞核之间的遗传变异很低。然而,基因组组装非常不完整,因此不能排除显著的核多样性。虽然核基因组的多样性仍未得到解决,但现在可以获得多个完整的线粒体基因组;分离株内部几乎没有变异,但它们之间有显著的变异。
HighlightsIn arbuscular mycorrhizal fungi, multiple nuclei share a common cytoplasm.There can be genomic diversity among the nuclei in an isolate.Changes in relative abundance of genetic variants can be accompanied by changes in phenotype.However, whole genome sequencing found only modest levels of variation.Mitochondrial genomes show even less within-isolate variation.Arbuscular mycorrhizal fungi (Glomeromycota) are the most widespread and important symbionts of plants. They cannot be cultured without plants, are apparently asexual, and have multiple nuclei in a common cytoplasm. There is evidence for genetic variation among nuclei, and for segregation of this variation during growth, but these findings remain contentious. Recently, two papers have reported whole genome sequences for a strain of Rhizophagus irregularis; both suggest that genetic variation among nuclei is low. Genome assembly is very incomplete, though, so significant nuclear diversity cannot be excluded. While the diversity of nuclear genomes remains unresolved, multiple complete mitochondrial genomes are now available; there is virtually no variation within isolates, but significant variation between them.
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