Quantitative proton MR techniques for measuring fat.
Quantitative proton MR techniques for measuring fat.
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DOI：
10.1002/nbm.3025
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发表时间：
2013-12
影响因子：
2.9
通讯作者：
Kan, H. E.
中科院分区：
文献类型：
--
作者：
Hu, H. H.;Kan, H. E.
关键词：
准确、精确和可靠的量化身体和器官脂肪分布的技术是生理学研究中的重要工具。它们在肥胖和涉及过量脂肪积累的疾病的研究中是迫切需要的。质子磁共振方法通过提供一系列基于弛豫法（T1，T2）和基于化学位移的方法来满足这一需求。这些技术可以生成区域和全身脂肪分布的信息可视化，测量特定身体仓库内的脂肪体积，并量化腹部器官和肌肉中的脂肪积累。MR方法通常用于研究脂肪在营养和代谢中的作用，测量短期和长期饮食和运动干预的有效性，研究脂肪在器官脂肪变性和肌营养不良中的意义，并阐明肥胖及其合并症的病理生理机制。本综述的目的是总结脂肪定量的主流MR策略。本文将简洁地描述区分水和脂肪质子信号的原理，总结各种技术的优点和局限性，并提供一些说明性示例。本文还将强调最近在棕色脂肪组织MR方面的努力，并简要讨论了一些未来的研究方向。
Accurate, precise, and reliable techniques for quantifying body and organ fat distributions are important tools in physiology research. They are critically needed in studies of obesity and diseases involving excess fat accumulation. Proton magnetic resonance methods address this need by providing an array of relaxometry-based (T1, T2) and chemical-shift-based approaches. These techniques can generate informative visualizations of regional and whole-body fat distributions, yield measurements of fat volumes within specific body depots, and quantify fat accumulation in abdominal organs and muscles. MR methods are commonly used to investigate the role of fat in nutrition and metabolism, to measure the efficacy of short and long-term dietary and exercise interventions, to study the implications of fat in organ steatosis and muscular dystrophies, and to elucidate pathophysiological mechanisms in the context of obesity and its comorbidities. The purpose of this review is to provide a summary of mainstream MR strategies for fat quantification. The article will succinctly describe the principles that differentiate water and fat proton signals, summarize advantages and limitations of various techniques, and offer a few illustrative examples. The article will also highlight recent efforts in MR of brown adipose tissue and conclude by briefly discussing some future research directions.
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影响因子：
3.3
作者：
Branca RT;Warren WS
通讯作者：
Warren WS
影响因子：
4.4
作者：
An, Li;van der Veen, Jan Willem;Li, Shizhe;Thomasson, David M.;Shen, Jun
通讯作者：
Shen, Jun
影响因子：
8.9
作者：
Cesari, Matteo;Fielding, Roger A.;Vellas, Bruno
通讯作者：
Vellas, Bruno
结合分子间双量子相干和 Dixon 水脂肪 MRI 绘制大鼠棕色脂肪组织图
影响因子：
2.9
作者：
Bao, Jianfeng;Cui, Xiaohong;Chen, Zhong
通讯作者：
Chen, Zhong
DOI：
10.1002/path.1700910126
发表时间：
1966-01-01
期刊：
JOURNAL OF PATHOLOGY AND BACTERIOLOGY
影响因子：
--
作者：
AHERNE, W;HULL, D
通讯作者：
HULL, D