Mapping tracts in the human subthalamic area by 11.7T ex vivo diffusion tensor imaging.
Mapping tracts in the human subthalamic area by 11.7T ex vivo diffusion tensor imaging.
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DOI：
10.1007/s00429-020-02066-x
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发表时间：
2020-05
影响因子：
3.1
通讯作者：
Lenz FA
中科院分区：
文献类型：
--
作者：
Oishi K;Mori S;Troncoso JC;Lenz FA
皮质-基底神经节-丘脑-皮质反馈回路由不同的白色物质通路组成，对于了解功能和解剖连接的体内成像研究以及在运动障碍（如帕金森病）的手术方法中定位丘脑底白色物质结构非常重要。动物中的连接组学分析已经确定了基底神经节和丘脑之间的纤维连接，这些纤维连接穿过Forel场，其中与运动、感觉和认知功能相关的其他纤维通路共存。我们现在报告这些途径在人类大脑的离体介观（250 μm）扩散张量成像和纤维束成像。这些神经束的位置是相对于相邻的灰质结构确定的，例如苍白球的内部和外部段;齿状回;丘脑底核;黑质网状部和齿状回;以及丘脑。人类丘脑底区的连接体图谱可作为影像学研究和神经外科计划的资源。
The cortico-basal ganglia-thalamo-cortical feedback loops that consist of distinct white matter pathways are important for understanding in vivo imaging studies of functional and anatomical connectivity, and for localizing subthalamic white matter structures in surgical approaches for movement disorders, such as Parkinson’s disease. Connectomic analysis in animals has identified fiber connections between the basal ganglia and thalamus, which pass through the fields of Forel, where other fiber pathways related to motor, sensory, and cognitive functions co-exist. We now report these pathways in the human brain on ex vivo mesoscopic (250 μm) diffusion tensor imaging and on tractography. The locations of the tracts were identified relative to the adjacent gray matter structures, such as the internal and external segments of the globus pallidus; the zona incerta; the subthalamic nucleus; the substantia nigra pars reticulata and compacta; and the thalamus. The connectome atlas of the human subthalamic region may serve as a resource for imaging studies and for neurosurgical planning.
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影响因子：
4.1
作者：
DeLong, Mahlon;Wichmann, Thomas
通讯作者：
Wichmann, Thomas
影响因子：
1.2
作者：
Chang, Eric H.;Argyelan, Miklos;Malhotra, Anil K.
通讯作者：
Malhotra, Anil K.
影响因子：
4.8
作者：
Calabrese E;Hickey P;Hulette C;Zhang J;Parente B;Lad SP;Johnson GA
通讯作者：
Johnson GA
影响因子：
2.5
作者：
APKARIAN, AV;HODGE, CJ
通讯作者：
HODGE, CJ
影响因子：
3.4
作者：
Calzavara, R;Zappalà, A;Luppino, G
通讯作者：
Luppino, G