Accuracy improvement of electrochemical whole blood ketone sensor based on HCT compensation algorithm
Accuracy improvement of electrochemical whole blood ketone sensor based on HCT compensation algorithm
复制标题
基于HCT补偿算法的电化学全血酮传感器精度提升
DOI：
10.1002/elps.201900472
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发表时间：
2020-04
期刊：
影响因子：
2.9
通讯作者：
Xiaobo Cen
中科院分区：
文献类型：
--
作者：
Ying Zhao;Hui Gu;Hongchun Li;Lei Huang;Xiaobo Cen
在此手稿中，我们证明了具有HCT（血细胞比容）补偿算法的电化学测试带，以提高血酮传感器的准确性。在传统的电化学传感器中，电化学电流直接解决
In this manuscript, we demonstrated an electrochemical test strip with HCT (hematocrit) compensation algorithm to improve the accuracy of blood ketone sensor. In the conventional electrochemical sensor, the electrochemical current was directly resolved into the concentration value of the determinant without HCT compensation. For lower or higher HCT blood sample, the measured result was inaccurate. In the proposed design, the blood impedance can be measured to estimate the HCT, which was utilized to compensate the electrochemical current to resolve the more accurate concentration of determinant. The practical blood sample tests demonstrated the proposed design can provide more believable and reliable measured result in clinical point‐of‐care setting.
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