Vaccines for porcine epidemic diarrhea virus and other swine coronaviruses.
Vaccines for porcine epidemic diarrhea virus and other swine coronaviruses.
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DOI:
10.1016/j.vetmic.2016.11.029
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发表时间:
2017-07
影响因子:
3.3
通讯作者:
Zakhartchouk A
中科院分区:
文献类型:
--
作者:
Gerdts V;Zakhartchouk A
Swine coronaviruses responsible for significant economic losses to the swine industry. Vaccines available only for TGEV and PEDV. Types of vaccines include inactivated, live attenuated, recombinant, vectored and DNA vaccines. Most vaccines aim to induce lactogenic immunity by immunizing sows at the end of gestation. The recent introduction of the porcine epidemic diarrhea virus (PEDV) into the North American swine herd has highlighted again the need for effective vaccines for swine coronaviruses. While vaccines for transmissible gastroenteritis virus (TGEV) have been available to producers around the world for a long time, effective vaccines for PEDV and deltacoronaviruses were only recently developed or are still in development. Here, we review existing vaccine technologies for swine coronaviruses and highlight promising technologies which may help to control these important viruses in the future.
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