A systematic review of prospective memory in HIV disease: from the laboratory to daily life.

A systematic review of prospective memory in HIV disease: from the laboratory to daily life.
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DOI:
10.1080/13854046.2017.1373860
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发表时间:
2018-07
期刊:
The Clinical neuropsychologist
影响因子:
--
通讯作者:
Woods SP
Woods SP
中科院分区:
其他
文献类型:
--
作者:
Avci G;Sheppard DP;Tierney SM;Kordovski VM;Sullivan KL;Woods SP

文献摘要

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前瞻记忆(Prospective Memory,PM)是一种在特定线索的作用下形成并保持意图的能力。神经损伤和相关的神经认知障碍在艾滋病毒感染者中很常见,因此他们可能容易受到PM的损害。本文献综述采用结构化的定性方法来总结和评估我们目前对艾滋病毒感染者PM功能的理解。33项在HIV+人群中进行的PM研究符合纳入标准。研究结果表明,艾滋病毒与PM的中度缺陷有关,这似乎在很大程度上独立于常见的共病因素。PM缺陷的模式揭示了与额叶系统病理学和相关的执行功能障碍相一致的策略过程的失调,其特征在于HIV相关的神经损伤。文献还表明,艾滋病毒相关的PM缺陷在广泛的健康行为(例如,药物治疗不依从性)和日常生活活动(例如,就业)。早期试图改善艾滋病毒疾病的预防性管理的尝试表明,支持战略过程对某些人可能是有效的。艾滋病毒相关的PM缺陷是常见的,并对感染者的日常生活和健康产生重大不利影响。还有很多工作要做,以了解艾滋病毒相关的PM赤字的认知结构和最有效的手段,以提高PM功能和改善艾滋病毒感染者的健康结果。
Prospective memory (PM) is described as the capacity to form and maintain an intention that is executed in response to a specific cue. Neural injury and associated neurocognitive disorders are common among persons living with HIV disease, who might therefore be susceptible to impairment in PM. This literature review utilized a structured qualitative approach to summarize and evaluate our current understanding of PM functioning in people living with HIV disease. 33 studies of PM in HIV+ persons met criteria for inclusion. Findings showed that HIV is associated with moderate deficits in PM, which appear to be largely independent of commonly observed comorbid factors. The pattern of PM deficits reveals dysregulation of strategic processes that is consistent with the frontal systems pathology and associated executive dysfunction that characterizes HIV-associated neural injury. The literature also suggests that HIV-associated PM deficits present a strong risk of concurrent problems in a wide range of health behaviors (e.g., medication non-adherence) and activities of daily living (e.g., employment). Early attempts to improve PM in HIV disease have revealed that supporting strategic processes might be effective for some individuals. HIV-associated PM deficits are common and exert a significant adverse effect on the daily lives and health of infected persons. Much work remains to be done to understand the cognitive architecture of HIV-associated PM deficits and the most efficient means to enhance PM functioning and improve health outcomes in persons living with HIV.
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