Human circadian pacemaker is sensitive to light throughout subjective day without evidence of transients.
Human circadian pacemaker is sensitive to light throughout subjective day without evidence of transients.
复制标题
人类昼夜节律起搏器在整个主观一天中对光敏感,没有瞬变的证据。
DOI:
10.1152/ajpregu.1997.273.5.r1800
复制
发表时间:
1997
期刊:
影响因子:
--
通讯作者:
Czeisler,CA
中科院分区:
文献类型:
--
作者:
Jewett,ME;Rimmer,DW;Duffy,JF;Klerman,EB;Kronauer,RE;Czeisler,CA
Fifty-six resetting trials were conducted across the subjective day in 43 young men using a three-cycle bright-light (∼10,000 lx) stimulus against a background of very dim light (10–15 lx). The phase-response curve (PRC) to these trials was assessed for the presence of a “dead zone” of photic insensitivity and was compared with another three-cycle PRC that had used a background of ∼150 lx. To assess possible transients after the light stimulus, the trials were divided into 43steady-statetrials, which occurred after several baseline days, and 13consecutivetrials, which occurred immediately after a previous resetting trial. We found that1) bright light induces phase shifts throughout subjective day with no apparent dead zone;2) there is no evidence of transients in constant routine assessments of the fitted temperature minimum 1–2 days after completion of the resetting stimulus; and3) the timing of background room light modulates the resetting response to bright light. These data indicate that the human circadian pacemaker is sensitive to light at virtually all circadian phases, implying that the entire 24-h pattern of light exposure contributes to entrainment.
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DOI:
10.1002/9780470514597.ch14
发表时间:
1995
期刊:
Ciba Foundation symposium
影响因子:
--
作者:
Czeisler,CA
通讯作者:
Czeisler,CA
DOI:
10.1073/pnas.44.9.965
发表时间:
1958-01-01
影响因子:
11.1
作者:
PITTENDRIGH, C;BRUCE, V;KAUS, P
通讯作者:
KAUS, P
影响因子:
3.5
作者:
P. Lakin
通讯作者:
P. Lakin
影响因子:
3.5
作者:
R. Kronauer;M. Jewett;C. Czeisler
通讯作者:
C. Czeisler
影响因子:
--
作者:
M. Moore;D. Kass;J. Herd
通讯作者:
J. Herd