Perspective: Dynamics of receptor tyrosine kinase signaling complexes.
Perspective: Dynamics of receptor tyrosine kinase signaling complexes.
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DOI:
10.1016/j.febslet.2012.05.002
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发表时间:
2012-08-14
期刊:
影响因子:
3.5
通讯作者:
Mayer BJ
中科院分区:
文献类型:
--
作者:
Mayer BJ
Textbook descriptions of signal transduction complexes provide a static snapshot view of highly dynamic events. Despite enormous strides in identifying the key components of signaling complexes and the underlying mechanisms of signal transduction, our understanding of the dynamic behavior of these complexes has lagged behind. Using the example of receptor tyrosine kinases, this perspective takes a fresh look at the dynamics of the system and their potential impact on signal processing.
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