Neuromuscular urethral function and urethral urodynamic parameters between urgency and stress incontinence do not differ.
Neuromuscular urethral function and urethral urodynamic parameters between urgency and stress incontinence do not differ.
复制标题
急迫性尿失禁和压力性尿失禁之间的神经肌肉尿道功能和尿道尿动力学参数没有差异。
DOI：
10.1007/s00192-021-04773-3
复制
发表时间：
2022
影响因子：
1.8
通讯作者：
Kenton,Kimberly
中科院分区：
文献类型：
--
作者：
Geynisman-Tan,Julia;Mou,Tsung;Mueller,MargaretG;Kenton,Kimberly
前言和假设用同心针肌电图仪(CNEMG)和尿动力学(UDS)参数描述和比较压力性尿失禁(SUI)和急迫性尿失禁(UUI)女性的尿路神经肌肉功能。方法从泌尿外科诊所招募尿失禁女性，如果她们对老龄化的医学、流行病学和社会方面问卷中的一项回答“有时”或“总是”。参与者根据MESA评分被分为应激性(SUI)或紧迫性(UUI)大小便失禁组。受试者使用美敦力多运动单位动作电位分析对三个插入点的横纹尿路括约肌进行CNEMG检查。用Laborie微尖导尿管进行UDS检查：分别在基线和300uml时测得尿压曲线，用SPSS软件进行统计学分析。连续变量比较采用独立t检验或Mann-Whitney U，分类变量比较采用卡方检验。结果56名女性(37名SUI，19名UUI)的平均 ± SD年龄为53 ± ，13岁。在基线水平，SUI患者更年轻，更有可能处于绝经前，BMI更低。UUI组和SUI组的尿路肌电参数和UDS参数无明显差异，但UUI组的最大膀胱容量低于SUI组。在对年龄、BMI和MCC进行Logistic回归分析后，SUI组和UUI组的EMG或UDS参数无差异。结论UUI和DO患者与SUI患者一样，表现出类似于SUI患者的尿道括约肌失神经再支配损伤。
Introduction and hypothesisTo describe and compare urethral neuromuscular function using concentric needle electromyography (CNEMG) and urodynamic (UDS) parameters between stress incontinent (SUI) and urge incontinent (UUI) women.MethodsIncontinent women were recruited from a urogynecology clinic if they answered “sometimes” or “always” to one of the items on the Medical, Epidemiologic, and Social Aspects of Aging questionnaire. Participants were categorized by MESA scores into stress (SUI) or urgency (UUI) incontinence groups. Participants underwent CNEMG of the striated urethral sphincter at three insertion sites using Medtronic multiple motor unit action potential analysis. UDS was performed with Laborie microtip catheters: urethral pressure profiles were obtained at baseline and 300 ml. Data were analyzed in SPSS. Continuous variables were compared with independent t-test or Mann-Whitney U, categorical variables with chi-square test. A logistic regression was performed to control for variables found to be significant on univariate analysis.ResultsFifty-six women (37 SUI, 19 UUI) with mean ± SD age of 53 ± 13 years participated. At baseline, patients with SUI were younger, more likely to be premenopausal and had lower BMIs. There were no differences in urethral EMG or UDS parameters between UUI and SUI women except lower maximum cystometric capacity in women with UUI. When controlling for age, BMI and MCC on logistic regression, there remained no differences between SUI and UUI groups on EMG or UDS parameters.ConclusionsWomen with UUI and DO show similar evidence of denervation-reinnervation injury to the striated urethral sphincter muscle as women with SUI.
登录
查看更多内容
无血清培养基中 SV40 转化的 BALB/c-3T3 细胞的贴壁独立集落形成：细胞和血清衍生因子的作用
影响因子：
64.5
作者：
D. Mcclure
通讯作者：
D. Mcclure
通过暴露于 N-甲基-N-硝基-N-亚硝基胍，在表达“椭圆形”细胞表型的培养的大鼠肝上皮细胞中诱导表型和核型变化。
DOI：
--
发表时间：
1985
期刊：
The American journal of pathology
影响因子：
--
作者：
Tsao,MS;Grisham,JW;Nelson,KG;Smith,JD
通讯作者：
Smith,JD
自发和化学转化大鼠肝细胞培养物中γ-谷氨酰转肽酶的表达
影响因子：
6.4
作者：
M. Miyazaki;S. Wahid;Keiko Miyano;Tamae Yabe;Jiro Sato
通讯作者：
Jiro Sato
对软琼脂生长和细胞表面特性作为成年大鼠肝上皮样细胞培养物转化标记的调查。
影响因子：
11.2
作者：
R. San;M. F. Laspia;A. Soiefer;C. J. Maslansky;J. Rice;G. Williams
通讯作者：
G. Williams
DOI：
10.1073/pnas.80.15.4684
发表时间：
1983-08
影响因子：
11.1
作者：
H. Marquardt;M. Hunkapiller;Leroy Hood;D. Twardzik;J. D. Larco;J. Stephenson;G. Todaro
通讯作者：
H. Marquardt;M. Hunkapiller;Leroy Hood;D. Twardzik;J. D. Larco;J. Stephenson;G. Todaro