Diversity Takes Shape: Understanding the Mechanistic and Adaptive Basis of Bacterial Morphology.

Diversity Takes Shape: Understanding the Mechanistic and Adaptive Basis of Bacterial Morphology.
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DOI:
10.1371/journal.pbio.1002565
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发表时间:
2016-10
期刊:
影响因子:
9.8
通讯作者:
Brun YV
Brun YV
中科院分区:
生物学1区
文献类型:
--
作者:
Kysela DT;Randich AM;Caccamo PD;Brun YV

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The modern age of metagenomics has delivered unprecedented volumes of data describing the genetic and metabolic diversity of bacterial communities, but it has failed to provide information about coincident cellular morphologies. Much like metabolic and biosynthetic capabilities, morphology comprises a critical component of bacterial fitness, molded by natural selection into the many elaborate shapes observed across the bacterial domain. In this essay, we discuss the diversity of bacterial morphology and its implications for understanding both the mechanistic and the adaptive basis of morphogenesis. We consider how best to leverage genomic data and recent experimental developments in order to advance our understanding of bacterial shape and its functional importance. The bacterial domain displays a spectacular diversity of cellular shape. This Essay explores our surprisingly limited understanding as to how and why these shapes have evolved and discusses ways in which this dearth of knowledge can be addressed.
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