Glaucoma and Antioxidants: Review and Update.

Glaucoma and Antioxidants: Review and Update.
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青光眼与抗氧化剂:综述与最新进展

DOI:
10.3390/antiox9111031
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发表时间:
2020-10-22
期刊:
Antioxidants (Basel, Switzerland)
影响因子:
--
通讯作者:
Del-Rio-Vellosillo M
Del-Rio-Vellosillo M
中科院分区:
其他
文献类型:
--
作者:
Garcia-Medina JJ;Rubio-Velazquez E;Lopez-Bernal MD;Cobo-Martinez A;Zanon-Moreno V;Pinazo-Duran MD;Del-Rio-Vellosillo M

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青光眼是一种以视网膜神经节细胞进行性变性为特征的神经退行性疾病。氧化应激与该病的细胞死亡有关。从理论上讲,这种有害后果可以通过抗氧化剂物质来减少。这篇综述的目的是收集有关抗氧化剂补充及其对青光眼影响的研究,并为读者提供这一领域的最新信息。为此,我们纳入了青光眼动物模型和临床试验的研究。虽然有不同的结果,但在青光眼中补充抗氧化剂可能是一种有前途的青光眼治疗方法。
Glaucoma is a neurodegenerative disease characterised by the progressive degeneration of retinal ganglion cells. Oxidative stress has been related to the cell death in this disease. Theoretically, this deleterious consequence can be reduced by antioxidants substances. The aim of this review is to assemble the studies published in relation to antioxidant supplementation and its effects on glaucoma and to offer the reader an update on this field. With this purpose, we have included studies in animal models of glaucoma and clinical trials. Although there are variable results, supplementation with antioxidants in glaucoma may be a promising therapy in glaucoma.
DOI: 10.1111/aos.13530
发表时间: 2018-03-01
影响因子: 3.4
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